Detection of Phenols in Drinking Water by Liquid Chromatography-electrospray Ionization-tandem Mass Spectrometry Using Dansyl Derivatization

DOI

Bibliographic Information

Other Title
  • ダンシルクロリド誘導体化-液体クロマトグラフィー／エレクトロスプレーイオン化タンデム質量分析法による水道水中フェノール類の測定

Abstract

<p>In this study, to develop a method for detecting phenols included in the Japanese drinking water quality standards, without using solid-phase extraction, a direct injection method based on liquid chromatography-electrospray ionization-tandem mass spectrometry (LC-ESI-MS/MS) using dansyl chloride (DNS-Cl) derivatization was examined. We developed a test method by adding an internal standard solution, carbonate buffer containing phosphoric acid, and DNS-Cl solution to sample water, derivatizing it at a reaction temperature of 60°C, and subjecting it to LC/MS/MS. To evaluate the validity of our method, a spike and recovery test was conducted using tap water dechlorinated by sodium ascorbate and dechlorinated tap water containing copper sulfate and phosphoric acid for sample preservation. The results of the recovery test indicated that two factors, namely the accuracy and repeatability of the calibration curve and the accuracy, repeatability, and intermediate precision of the recovery test, satisfied the Japanese validation guidelines on drinking water analysis. Thus, this method can be useful for detecting phenols in drinking water.</p>

Journal

  • ENVIRONMENTAL SCIENCE

    ENVIRONMENTAL SCIENCE 35 (2), 94-102, 2022-03-31

    SOCIETY OF ENVIRONMENTAL SCIENCE, JAPAN

Keywords

Details 詳細情報について

  • CRID
    1390010292814617216
  • DOI
    10.11353/sesj.35.50
  • ISSN
    18845029
    09150048
  • Text Lang
    ja
  • Data Source
    • JaLC
  • Abstract License Flag
    Disallowed

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