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- 吉澤 拓也
- 立命館大学生命科学部
書誌事項
- タイトル別名
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- Phase Regulation of RNA Binding Protein
抄録
<p>Living cells utilize liquid-liquid phase separation (LLPS) to enable the compartmentalization of macromolecules as membrane-less organelles. RNA binding proteins with intrinsically disordered regions play a central role in the biological LLPS. Although LLPS provides an enormous advantage in a mixture of a wide variety of biological macromolecules, misregulation leads to fatal diseases, including Amyotrophic Lateral Sclerosis (ALS). Phase state of RNA binding protein FUS and its regulation by nuclear import receptor karyopherinβ2 will be discussed.</p>
収録刊行物
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- 日本結晶学会誌
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日本結晶学会誌 64 (2), 140-147, 2022-05-31
日本結晶学会
- Tweet
キーワード
詳細情報 詳細情報について
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- CRID
- 1390010776369127296
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- ISSN
- 18845576
- 03694585
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- 本文言語コード
- ja
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- データソース種別
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- JaLC
- Crossref
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- 抄録ライセンスフラグ
- 使用不可