Dyslipidemia, a common complication in obese children

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  • Hara Mitsuhiko
    Tokyo Kasei Gakuin University
  • Saito Emiko
    Tokyo Kasei Gakuin University
  • Abe Yuriko
    Medical Education Center, Nihon University School of Medicine, Tokyo, Japan
  • Okada Tomoo
    Department of Nutrition and Life Science, Kanagawa Institute of Technology, Kanagawa, Japan

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Other Title
  • 肥満小児に合併しやすい脂質異常症
  • ヒマン ショウニ ニ ガッペイ シヤスイ シシツ イジョウショウ

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Abstract

Obese children suffer from a variety of complications. Among them, dyslipidemia is one of the most common complications. There are gender and age differences in serum TC and HDL-C levels in children. And as obesity becomes more severe, the lipid profile tends to be more atherosclerosis-inducing. Therefore, obesity treatment from childhood and correction of dyslipidemia associated with obesity are necessary for the primary prevention of cardiovascular disease. Since the diagnostic criteria for dyslipidemia differ between adults and children, it is necessary to use the diagnostic criteria for children. There are two types of dyslipidemia: primary dyslipidemia and secondary dyslipidemia, specifically, hyper-LDL-cholesterolemia, hypertriglyceridemia, and hypo-HDL-cholesterolemia. Familial hypercholesterolemia（ FH） is the most common cause of primary hyperlipidemia, but many cases of FH are not associated with obesity. On the other hand, secondary dyslipidemias that tend to be associated with obesity are hypertriglyceridemia and hypo-HDL-cholesterolemia. The treatment of these dyslipidemias is to correct excessive intake of simple sugars and carbohydrates, and to actively consume n-3 polyunsaturated fatty acids. For hypo-HDL-cholesterolemia, exercise is recommended in addition to dietary guidance.

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