A case of intravascular large B-cell lymphoma manifested as lacunar infarction

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Other Title
  • ラクナ梗塞様症状で発症し血管内大細胞型B細胞リンパ腫と診断した1例

Abstract

<p>A 79-year-old man was admitted to our hospital because of sudden onset of left ataxic hemiparesis. Brain MRI diffusion weighted images showed typical lacunar infarction on the right internal capsule. He had no risk factors of cerebrovascular disorder such as hypertension, diabetes mellitus, hyperlipidemia and arrhythmia. On admission, he had a slight fever and his laboratory data showed anemia, thrombocytopenia and elevation of CRP and LDH. Intravascular large B-cell lymphoma (IVLBCL) was suspected because the serum level of soluble IL-2 receptor was also elevated. Pathological diagnosis of IVLBCL was underwent by the skin biopsy from his senile hemangiomas. Although IVLBCL was known to demonstrate various CNS lesions, it is extremely rare to be manifested as a single lacunar infarction, and this case must be important for the differential diagnosis.</p>

Journal

  • Rinsho Shinkeigaku

    Rinsho Shinkeigaku 62 (6), 492-495, 2022

    Societas Neurologica Japonica

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