A Case of Successful FTD/TPI for Postoperative Recurrence of Signet-ring Cell Carcinoma of the Ascending Colon
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- Hagiwara Chie
- Department of Surgery, Ageo Central General Hospital Department of Colorectal Surgery, Kitasato University School of Medecine
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- Tsutsui Atsuko
- Department of Surgery, Ageo Central General Hospital Department of Colorectal Surgery, Kitasato University School of Medecine
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- Nakanishi Ryo
- Department of Surgery, Ageo Central General Hospital Department of Colorectal Surgery, Kitasato University School of Medecine
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- Osada Hiromi
- Department of Pathology, Ageo Central General Hospital
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- Sugitani Masahiko
- Department of Pathology, Ageo Central General Hospital
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- Naito Takeshi
- Department of Colorectal Surgery, Kitasato University School of Medecine
Bibliographic Information
- Other Title
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- 上行結腸印環細胞癌切除後再発例に対してFTD/TPI療法が奏効した1例
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Abstract
<p>The patient was an 80-year-old man. He visited our hospital because elevated tumor marker levels were noted during a physical examination. Lower gastrointestinal endoscopy showed a type 0-IIa lesion in the ascending colon, and a biopsy indicated the presence of adenocarcinoma (por/sig). A computed tomography scan showed many enlarged lymph nodes in the ileocecum. Therefore, he was diagnosed as having a cT1bN2bM0-stage ascending colon carcinoma. On performing laparoscopic ileocecal resection, a 20-mm-large mass was detected in the subserosa of the resected tissue. It was identified as a lymph node that had enlarged due to metastasis of the mucinous carcinoma. On performing additional resection, a signet-ring cell carcinoma lesion was detected in the ascending colon near the metastatic site. Therefore, the patient was diagnosed as having a pT3 (Ly) N2bM0-stage ascending colon carcinoma. After adjuvant chemotherapy with CAPOX, paratracheal lymph node metastasis and peritoneal dissemination recurrence were confirmed. However, after switching to FTD/TPI, the peritoneal dissemination reduced and tumor marker levels normalized. Although signet-ring cell carcinoma of the colon is rare and often difficult to treat, we experienced a patient who was successfully treated after recurrence. Thus, we report this case, with a review of the literature.</p>
Journal
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- Nippon Daicho Komonbyo Gakkai Zasshi
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Nippon Daicho Komonbyo Gakkai Zasshi 75 (8), 409-414, 2022
The Japan Society of Coloproctology
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Keywords
Details 詳細情報について
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- CRID
- 1390011461951297280
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- ISSN
- 18829619
- 00471801
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- Text Lang
- ja
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- Data Source
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- JaLC
- Crossref
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- Abstract License Flag
- Disallowed