Clinical Experience with Treatments of Gastric Neuroendocrine Neoplasms
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- SHINOHARA Yoshihito
- Department of Gastroenterological Surgery II, Hokkaido University Faculty of Medicine
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- TSUCHIKAWA Takahiro
- Department of Gastroenterological Surgery II, Hokkaido University Faculty of Medicine
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- EBIHARA Yuma
- Department of Gastroenterological Surgery II, Hokkaido University Faculty of Medicine
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- SHICHINOHE Toshiaki
- Department of Gastroenterological Surgery II, Hokkaido University Faculty of Medicine
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- HIRANO Satoshi
- Department of Gastroenterological Surgery II, Hokkaido University Faculty of Medicine
Bibliographic Information
- Other Title
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- 胃原発神経内分泌腫瘍の治療経験
- イ ゲンパツ シンケイ ナイブンピ シュヨウ ノ チリョウ ケイケン
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Abstract
<p>In this study, we aimed to clarify the clinical features of gastric neuroendocrine neoplasms (NENs).</p><p>We retrospectively analyzed clinicopathological parameters and clinical outcomes of a total of 12 patients treated with the diagnosis of gastric NEN in Hokkaido University Hospital from November 2016 to April 2020.</p><p>Of the 12 patients with gastric NEN, ten had neuroendocrine tumor (NET) and two had neuroendocrine cancer (NEC). Of 10 NET patients, six had Rindi type I, two had Rindi type II, and two had Rindi type III. There were eight hypergastrinemia patients. As to treatments selected by the Rindi classification, type I patients underwent total gastrectomy (n=1), distal gastrectomy (n=1), partial resection (n=2), endoscopic dissection (n=1) and observation (n=1), and all six have been alive with no recurrence. One type II patient has been kept in observation for other diseases, and another one is undergoing a somatostain analog for unresectable liver metastases. The both type III patients underwent partial resection and proximal gastrectomy with no recurrence. One NEC patient died for sepsis and another one selected palliative therapy. In conclusion, we should decide the treatment of gastric NENs, which manifest in a variety of pathologic conditions, according to the Rindi classification.</p>
Journal
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- Nihon Rinsho Geka Gakkai Zasshi (Journal of Japan Surgical Association)
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Nihon Rinsho Geka Gakkai Zasshi (Journal of Japan Surgical Association) 83 (2), 263-267, 2022
Japan Surgical Association
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Details 詳細情報について
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- CRID
- 1390011782480659328
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- NII Book ID
- AA11189709
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- ISSN
- 18825133
- 13452843
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- NDL BIB ID
- 032022607
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- Text Lang
- ja
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- Data Source
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- JaLC
- NDL
- Crossref
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- Abstract License Flag
- Disallowed