Resected case of cholesterol granuloma in anterior mediastinum with high standardized uptake value max on <sup>18</sup>F-fluorodeoxyglucose positron emission tomography

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  • Kita Yusuke
    Department of Thoracic Surgery, Omi Medical Center
  • Hayashi Kazuki
    Department of Thoracic Surgery, Omi Medical Center
  • Hanaoka Jun
    Division of General Thoracic Surgery, Department of Surgery, Shiga University of Medical Science

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Other Title
  • FDG-PETでSUV maxが高値を示した縦隔コレステリン肉芽腫の1手術例

Abstract

<p>Cholesterol granuloma is a type of foreign body granuloma that forms in reaction to cholesterol crystals. This is a well-studied condition affecting the middle ear and paranasal sinuses, whereas other lesions are rare.</p><p>We report a cholesterol granuloma in the anterior mediastinum of a 55-year-old asymptomatic man. Chest computed tomography showed a 45 × 25-mm multilocular nodular lesion in the anterior mediastinum. T1- and T2-weighted magnetic resonance images revealed hypo-intense signals with a contrast effect. Positron emission tomography computed tomography showed 18F-fluorodeoxyglucose uptake with a maximum standardized uptake value of 9.4. Therefore, malignant diseases, including thymic cancer and lymphoma were considered for a pre-operative diagnosis.</p><p>Video-assisted thoracic surgery was conducted for diagnosis and therapeutic purposes. The pathological diagnosis was a cholesterol granuloma, which originated from the thymus.</p>

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