The role of thymic stromal lymphopoietin (TSLP) in asthma

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  • 【投稿/レビュー】気管支喘息におけるthymic stromal lymphopoietin（TSLP）の役割

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Thymic stromal lymphopoietin (TSLP) is a cytokine produced by airway epithelial cells that initiate airway inflammation in response to allergens, microorganisms, pollutants, and other stimuli. TSLP acts on a variety of immune cells related to asthma pathophysiology, and is strongly implicated not only in the induction but also in the aggravation and perpetuation of airway inflammation. Here, we review the molecular mechanisms of TSLP in airway inflammation and its role in bronchial asthma.

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