Early Outcomes of Intuity Rapid Deployment Aortic Valve Replacement Compared With Conventional Biological Valves in Japanese Patients

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  • Ono Yoshikazu
    Department of Cardiac Surgery, National Cerebral and Cardiovascular Center
  • Yajima Shin
    Department of Cardiac Surgery, National Cerebral and Cardiovascular Center
  • Kainuma Satoshi
    Department of Cardiac Surgery, National Cerebral and Cardiovascular Center
  • Kawamoto Naonori
    Department of Cardiac Surgery, National Cerebral and Cardiovascular Center
  • Tadokoro Naoki
    Department of Cardiac Surgery, National Cerebral and Cardiovascular Center
  • Kakuta Takashi
    Department of Cardiac Surgery, National Cerebral and Cardiovascular Center
  • Koga-Ikuta Ayumi
    Department of Cardiac Surgery, National Cerebral and Cardiovascular Center
  • Fujita Tomoyuki
    Department of Cardiac Surgery, National Cerebral and Cardiovascular Center
  • Fukushima Satsuki
    Department of Cardiac Surgery, National Cerebral and Cardiovascular Center

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<p>Background: This study aimed to elucidate the short-term surgical outcomes and hemodynamics of the Intuity valve compared to the standard bioprosthesis in Japanese patients.</p><p>Methods and Results: Among the 307 consecutive patients who underwent aortic valve replacement (AVR) between February 2019 and March 2021, the Intuity valve was implanted in 95 patients (Intuity group) and a conventional stented bioprosthesis was implanted in 193 patients (conventional group). After propensity score matching, there was no significant difference in in-hospital mortality between the Intuity (n=2, 3%) and conventional groups (n=0, P=0.490). Operation, cardiopulmonary bypass, and aortic cross-clamping times were significantly shorter in the Intuity group. Although the effective orifice area index, trans-prosthetic mean pressure gradient, and peak velocity were similar between the 2 groups at 1 week postoperatively, the Intuity group showed a better mean pressure gradient and peak velocity at 1 year postoperatively. Complete atrioventricular block requiring permanent pacemaker implantation developed in 2 patients (3%) in the Intuity group and none in the conventional group (P=0.476). Mild or greater paravalvular leakage was present in 8 patients (13%) in the Intuity group and 2 patients (3%) in the conventional group (P=0.095).</p><p>Conclusions: AVR using the Intuity valve in Japanese patients is satisfactory, with a better valve performance and a low incidence of complete atrioventricular block at 1 year postoperatively.</p>

収録刊行物

  • Circulation Journal

    Circulation Journal 86 (11), 1710-1718, 2022-10-25

    一般社団法人 日本循環器学会

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