Usefulness of endoscopic sclerotherapy with N-butyl-2-cyanoacrylate for perforating vein closure in esophageal varices
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- Kudo Koichi
- Department of Gastroenterology, Saiseikai Kumamoto Hospital
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- Morita Muneshin
- Department of Gastroenterology, Saiseikai Kumamoto Hospital
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- Ieki Ukito
- Department of Gastroenterology, Saiseikai Kumamoto Hospital
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- Kojima Norihiro
- Department of Gastroenterology, Saiseikai Kumamoto Hospital
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- Kadono Yoshihiro
- Department of Gastroenterology, Saiseikai Kumamoto Hospital
Bibliographic Information
- Other Title
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- 食道静脈瘤の貫通静脈閉鎖にN-butyl-2-cyanoacrylateを併用した内視鏡的硬化療法
- ショクドウ ジョウミャクリュウ ノ カンツウ ジョウミャク ヘイサ ニ N-butyl-2-cyanoacrylate オ ヘイヨウ シタ ナイシキョウテキ コウカ リョウホウ
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Abstract
<p>In endoscopic sclerotherapy for esophageal varices, perforating veins can interfere with hemostasis during treatment and cause difficulties in completing the procedure, leading to short-term recurrence. We devised a method for closing perforating veins identified by preoperative ultrasonic endoscopy with N-butyl-2-cyanoacrylate (NBCA) to enable conventional sclerotherapy. In total, there were 22 patients with a preoperatively identified perforating vein; 9 cases were closed with NBCA (Group A), and 13 cases were closed by other means (ethanol, endoscopic ligation, balloon tamponade) (Group B); these groups were compared The average dose of sclerosant was significantly lower in Group A (8.3 ml) compared to group B (12.2 ml, p=0.038). The consolidation rate after 3 months was also significantly lower in group A (22.2% in group A vs. 76.9% in group B, p=0.036). Group A also had shorter treatment times, less treatment frequency, and fewer hospital days than B group and showed better results in invasiveness and treatment content. Using NBCA for perforating vein closure enabled reliable hemostasis, safe completion of a series of sclerotherapy procedures, and improved curative possibility.</p>
Journal
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- Japanese Journal of Portal Hypertension
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Japanese Journal of Portal Hypertension 26 (1), 29-34, 2020
The Japan Society for Portal Hypertension
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Keywords
Details 詳細情報について
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- CRID
- 1390013098760541696
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- NII Article ID
- 40022226589
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- NII Book ID
- AA11349565
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- ISSN
- 21866376
- 13448447
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- NDL BIB ID
- 030402102
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- Text Lang
- ja
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- Data Source
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- JaLC
- NDL
- CiNii Articles
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- Abstract License Flag
- Disallowed