Efficacy of Ki-67 immunostaining in the diagnosis of primary myoepithelial carcinoma of the parotid gland after surgery for metastatic lung tumor: A case report

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  • 耳下腺多形腺腫由来筋上皮癌及びその肺転移の診断にKi-67の免疫染色が有用であった一例

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Abstract

<p>A 74-year-old woman underwent surgery for a parotid tumor 7 years earlier and was histologically diagnosed with pleomorphic adenoma. She had a medical history of Sjögren's syndrome and scleroderma and was under observation for enlargement of multiple lung nodules. CT revealed pulmonary nodules measuring 1.0 cm in the S1+2 left upper lobe, 1.4 cm in the S8 left lower lobe, and 0.6 cm in the S2 right upper lobe. All of these showed high FDG accumulation on PET-CT. First, wedge resection of the S8 and S1+2 left lung was performed, and after 3 months, wedge resection of the S2 right lung was performed. Pathological re-evaluation revealed parotid tumors that appeared 7 years before and metastases were diagnosed as myoepithelial carcinoma ex pleomorphic adenoma, and immunostaining for Ki-67 was critical in the diagnosis. We report a case of myoepithelial carcinoma ex pleomorphic adenoma with a review of the literature.</p>

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