A case of colchicine poisoning caused by accidental ingestion of <i>Gloriosa superba</i>
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- Inaba Daichi
- Emergency and Critical Care Center, Kagoshima City Hospital
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- Sugimoto Ryuji
- Emergency and Critical Care Center, Kagoshima City Hospital
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- Yasutake Yuki
- Emergency and Critical Care Center, Kagoshima City Hospital
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- Kamimura Yoshio
- Emergency and Critical Care Center, Kagoshima City Hospital
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- Yoshizawa Tomohiro
- Clinical Toxicology Center, Saitama Medical University
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- Hanazawa Tomoki
- Clinical Toxicology Center, Saitama Medical University
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- Yoshihara Hideaki
- Emergency and Critical Care Center, Kagoshima City Hospital
Bibliographic Information
- Other Title
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- グロリオサ誤食によるコルヒチン中毒の1例
- グロリオサ ゴショク ニ ヨル コルヒチン チュウドク ノ 1レイ
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Abstract
<p>Colchicine, which is used as a remedy for gout, is found in some plants, including Gloriosa superba. Gloriosa superba is a member of the family Colchicaceae and is sold commercially as an ornamental plant. In this study, we describe a case of colchicine poisoning caused by accidental ingestion of Gloriosa superba. The patient, an 84-year-old man, developed symptoms of vomiting and diarrhea. The next day, he was admitted to our hospital owing to suspicion of acute enteritis. On the second day of hospitalization, he experienced disturbed consciousness and lactic acidosis. On the third day of hospitalization, he died, despite intensive care. Additional interviews with the family revealed that he accidentally ate a bulb of Gloriosa superba before the appearance of gastrointestinal symptoms. Subsequent investigation revealed the presence of colchicine in his urine and blood and he was diagnosed with colchicine poisoning caused by ingestion of Gloriosa superba. Colchicine poisoning can cause rapid multi-organ damage depending on the amount ingested, and can be fatal. Symptoms of poisoning are nonspecific, and measurement of colchicine levels is time-consuming. Therefore, a detailed interview is extremely important for diagnosis.</p>
Journal
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- Japanese Journal of Clinical Toxicology
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Japanese Journal of Clinical Toxicology 35 (4), 319-324, 2022-12-10
Japanese Society for Clinical Toxicology
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Details 詳細情報について
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- CRID
- 1390013419523578752
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- NII Book ID
- AN10064448
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- ISSN
- 27582140
- 09143777
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- NDL BIB ID
- 032581992
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- Text Lang
- ja
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- Data Source
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- JaLC
- NDL
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- Abstract License Flag
- Allowed