A single-center retrospective study of the effects of steroid administration to pregnant women with expected preterm labor

IDA Kohei, KAWASAKI Kaoru, MORIUCHI Kaori, OHSUGA Takuma, MATSUZAKA Yu, TAKI Mana, YAMAGUCHI Ayaka, CHIGUSA Yoshitsugu, MOGAMI Haruta, KONDO Eiji, MANDAI Masaki

doi:10.11437/sanpunosinpo.75.32

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Late Pretermにおける経母体ステロイド投与の効果についての単施設後方視的検討
Late Preterm ニオケルケイボタイステロイドトウヨノコウカニツイテノタンシセツコウホウシテキケントウ

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Abstract

<p>Administration of corticosteroids to pregnant women who are expected to deliver in late preterm has been reported to reduce neonatal respiratory complications, but in Japan guidelines for administration have not been established. The purpose of this study was to evaluate the efficacy of corticosteroids administration in late preterm. 49 cases of late preterm labor without steroids from 2014 to 2015 (non-treated group) and 31 cases of late preterm labor with steroids from 2016 to 2020 (treated group) were statistically compared. There was no significant difference in the incidence of TTN (Transient tachypnea of the newborn), RDS (respiratory distress syndrome) and surfactant treatment between the two groups. The incidence of neonatal hypoglycemia was not significantly different between the two groups. There were no maternal complications due to steroid administration. This single-center retrospective study did not demonstrate the effect of antenatal steroid treatment in late preterm. Future multicenter prospective studies are required to establish evidence for antenatal steroid treatment in late preterm in Japan. [Adv Obstet Gynecol, 75(1) : 32-38, 2023 (R5.2)]</p>

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ADVANCES IN OBSTETRICS AND GYNECOLOGY

ADVANCES IN OBSTETRICS AND GYNECOLOGY 75 (1), 32-38, 2023-02-01

THE OBSTETRICAL GYNECOLOGICAL SOCIETY OF KINKI DISTRICT JAPAN

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