Establishment of a Core Outcome Set for Burn Care Research: Development and International Consensus

DOI
  • Young Amber
    Centre for Surgical Research, Population Health Sciences, Bristol Biomedical Research Centre, Bristol Medical School, University of Bristol, Bristol, UK
  • Davies Anna
    Centre for Surgical Research, Population Health Sciences, Bristol Biomedical Research Centre, Bristol Medical School, University of Bristol, Bristol, UK
  • Tsang Carmen
    Centre for Surgical Research, Population Health Sciences, Bristol Biomedical Research Centre, Bristol Medical School, University of Bristol, Bristol, UK
  • Kirkham Jamie
    Division of Population Health, Health Services Research & Primary Care, University of Manchester, Manchester, UK
  • Potokar Tom
    Centre for Global Burn Injury Policy and Research, Swansea University, Swansea, UK
  • Gibran Nicole
    UW Medicine Regional Burn Center, Harborview Medical Center, UW Department of Surgery, University of Washington (UW), Seattle, WA, USA
  • Tyack Zephanie
    Child Health Research Centre, Faculty of Medicine, Centre for Children’s Burns and Trauma Research, Queensland University of Technology, Brisbane, QLD, Australia
  • Meirte Jill
    Department of Medicine and Health Sciences, University of Antwerp, Antwerpen, Belgium
  • Harada Teruichi
    Department of Plastic Surgery, Teramoto Memorial Hospital, Kawachinagano, Osaka, Japan
  • Dheansa Baljit
    Department of Plastic Surgery and Burns, Queen Victoria Hospital, East Grinstead, UK
  • Dumville Jo
    Division of Population Health, Health Services Research & Primary Care, University of Manchester, Manchester, UK Division of Nursing, Midwifery, and Social Work, University of Manchester, Manchester, UK
  • Metcalfe Chris
    Bristol Medical School, University of Bristol, Bristol, UK
  • Ahuja Rajeev
    Department of Burns & Plastic Surgery, Lok Nayak Hospital and Maulana Azad Medical College, New Delhi, India
  • Wood Fiona
    Burn Service, University of Western Australia, Perth, WA, Australia
  • Gaskell Sarah
    Paediatric Psychosocial Service, Royal Manchester Children’s Hospital, Manchester, UK
  • Brookes Sara
    Institute of Cancer and Genomic Sciences, University of Birmingham, Birmingham, UK
  • Smailes Sarah
    Department of Physiotherapy, Broomfield Hospital, Mid Essex Hospitals, Chelmsford, UK
  • Jeschke Marc
    Department of Surgery and Plastic Surgery, Sunnybrook Research Institute, University of Toronto, Toronto, ON, Canada
  • Ali Cinar Murat
    Department of Physical Therapy and Rehabilitation, Hasan Kalyoncu University, Gaziantep, Turkey
  • Zia Nukhba
    Johns Hopkins International Injury Research Unit, Johns Hopkins University Bloomberg School of Public Health, Baltimore, MD, USA
  • Moghazy Amr
    Department of Plastic Surgery, Suez Canal University, Ismailia, Egypt
  • Mathers Jonathan
    Institute of Applied Health Research, University of Birmingham, Birmingham, UK
  • Falder Sian
    Department of Plastic Surgery, Alder Hey Children’s NHS Foundation Trust, Liverpool, UK
  • Edgar Dale
    Adult Burns Unit, Fiona Stanley Hospital, Murdoch, WA, Australia
  • Mary Blazeby Jane
    Centre for Surgical Research, Population Health Sciences, Bristol Biomedical Research Centre, Bristol Medical School, University of Bristol, Bristol, UK
  • Harada Translator: Teruichi
    Department of Plastic Surgery, Teramoto Memorial Hospital, Kawachinagano, Osaka, Japan

Bibliographic Information

Other Title
  • 熱傷治療研究におけるコア・アウトカム・セットの選定：その作成過程および国際コンセンサス

Abstract

<p> OBJECTIVE: To develop a core outcome set for international burn research.<br> DESIGN: Development and international consensus, from April 2017 to November 2019.<br> METHODS: Candidate outcomes were identified from systematic reviews and stakeholder interviews. Through a Delphi survey, international clinicians, researchers, and UK patients prioritised outcomes. Anonymised feedback aimed to achieve consensus. Pre-defined criteria for retaining outcomes were agreed. A consensus meeting with voting was held to finalise the core outcome set.<br> RESULTS: Data source examination identified 1021 unique outcomes grouped into 88 candidate outcomes. Stakeholders in round 1 of the survey, included 668 health professionals from 77 countries (18% from low or low middle income countries) and 126 UK patients or carers. After round 1, one outcome was discarded, and 13 new outcomes added. After round 2, 69 items were discarded, leaving 31 outcomes for the consensus meeting. Outcome merging and voting, in two rounds, with prespecified thresholds agreed seven core outcomes: death, specified complications, ability to do daily tasks, wound healing, neuropathic pain and itch, psychological wellbeing, and return to school or work.<br> CONCLUSIONS: This core outcome set caters for global burn research, and future trials are recommended to include measures of these outcomes.</p>

Journal

Keywords

Details 詳細情報について

  • CRID
    1390013950050858496
  • DOI
    10.34366/jburn.49.1_1
  • ISSN
    24351571
    0285113X
  • Text Lang
    ja
  • Data Source
    • JaLC
  • Abstract License Flag
    Disallowed

Report a problem

Back to top