Can environmental interventions aimed to reduce passive smoking prevent allergies?

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  • 環境介入（受動喫煙）によりアレルギーは予防できるのか

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<p>Passive smoking is associated with the risk of decreased respiratory function as well as the onset and severity of asthma in children. It is also associated with elevated total IgE levels and sensitization to food and inhalant allergens. Maternal smoking during pregnancy negatively affects fetal lung development and leads to decreased respiratory function after birth. In addition, it elevates the risks of decreased respiratory function and severe asthma in school-aged children. Passive smoking in pregnant women reduces the number of regulatory T cells in umbilical cord blood by epigenetic mechanisms, thus increasing the risk of atopic dermatitis, allergen sensitization, and wheezing during infancy. Evidence indicates that passive smoking increases disease risk due to exposure to tobacco smoke, and any interventions that legislate prevention of passive smoking decrease disease risk. Notably, the current global standard is that people are protected by legislations with penalties that were established based on the WHO Framework Convention on Tobacco Control (FCTC), which bans smoking in all public places. The risk of allergic diseases caused by passive smoking can be prevented or reduced by achieving the goals of the FCTC and maintaining an appropriate smoke-free environment consistently from the fetal period to adulthood.</p>

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