A case of multiple myeloma with plasmacytoma in the gallbladder and pancreas
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- Gibo Noriaki
- Department of Gastroenterology, Nagoya University Graduate School of Medicine Department of Gastroenterology, Daido Hospital
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- Nonogaki Koji
- Department of Gastroenterology, Daido Hospital
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- Ohno Eizaburo
- Department of Gastroenterology, Nagoya University Graduate School of Medicine
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- Aoki Toshinori
- Department of Gastroenterology, Nagoya University Graduate School of Medicine
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- Yashika Jun
- Department of Gastroenterology, Nagoya University Graduate School of Medicine
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- Uetsuki Kota
- Department of Gastroenterology, Nagoya University Graduate School of Medicine
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- Iida Tadashi
- Department of Gastroenterology, Nagoya University Graduate School of Medicine
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- Mizutani Yasuyuki
- Department of Gastroenterology, Nagoya University Graduate School of Medicine
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- Yamao Kentaro
- Department of Gastroenterology, Nagoya University Graduate School of Medicine
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- Ishikawa Takuya
- Department of Gastroenterology, Nagoya University Graduate School of Medicine
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- Uno Yusuke
- Department of Surgery, Daido Hospital
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- Kawashima Hiroki
- Department of Gastroenterology, Nagoya University Graduate School of Medicine
Bibliographic Information
- Other Title
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- 胆嚢及び膵臓に形質細胞腫を伴った多発性骨髄腫の1例
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Description
<p>An 84-year-old man presented to our hospital with back pain and loss of appetite, and was noted to have hypercalcemia, renal failure, and hyperproteinemia. The patient was diagnosed with multiple myeloma following bone marrow aspiration. Contrast-enhanced computed tomography revealed an irregular mass that was slightly contrast-enhanced in the gallbladder neck. A round mass with the same contrast effect was also noted in the pancreatic tail, right thoracic cavity, and abdominal cavity. Endoscopic ultrasonography showed that the gallbladder lesion was irregular hypoechoic mass combined with high and low echoes and the pancreatic tail lesions was irregular hypoechoic mass with clear contours. Fine needle aspiration under endoscopic ultrasonography was conducted on both lesions and showed plasma cells with atypia in both samples and were ultimately diagnosed as plasmacytoma. First-line bortezomib-melphalan-prednisone therapy had no response, and an obstructive jaundice associated with the growth of the gallbladder mass developed. However, second-line lenalidomide-dexamethasone therapy that was initiated after bile duct stenting showed a decrease in the M protein and improvement in hypercalcemia. Moreover, the gallbladder lesion and pancreatic lesion were reduced in size, which were consistent with the clinical course of plasmacytoma.</p>
Journal
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- Tando
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Tando 37 (1), 83-90, 2023-03-31
Japan Biliary Association
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Details 詳細情報について
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- CRID
- 1390014128339481472
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- ISSN
- 18836879
- 09140077
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- Text Lang
- ja
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- Data Source
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- JaLC
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- Abstract License Flag
- Disallowed