Development of DDS using extracellular vesicles

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Other Title
  • 細胞外小胞を利用したDDSの開発

Abstract

Extracellular Vesicles（EVs） are endogenous delivery carriers that deliver endogenous substances such as nucleic acids and proteins to the cells that take up EVs. Because of their nature as endogenous delivery carriers, development of EV-based DDS is expected. For the development of EV-based DDS, it is necessary to develop methods to produce and collect EVs, to load drugs onto EVs, and to control the pharmacokinetics of EVs in the body. Numerous research groups, including the author’s research group, have conducted research aimed at developing these methods. In this article, we would like to introduce the results of these studies that have been conducted toward the development of EV-based DDS, as well as the future prospects.

Journal

  • Drug Delivery System

    Drug Delivery System 38 (1), 58-66, 2023-01-25

    THE JAPAN SOCIETY OF DRUG DELIVERY SYSTEM

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