Survey of Magnesium Oxide Tablet Usage in Japan Using NDB Open Data
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- Ishimura Atsushi
- Division of Practical Pharmacy, Nihon Pharmaceutical University
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- Shimizu Yutaka
- Pharmaceutical department, Sainokumi Higashiomiya Medical Center
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- Onishi Ayano
- Division of Practical Pharmacy, Nihon Pharmaceutical University
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- Yabuki Naohiro
- Pharmaceutical department, Sainokumi Higashiomiya Medical Center
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- Matsuda Yoshikazu
- Division of Practical Pharmacy, Nihon Pharmaceutical University
Abstract
Magnesium oxide, a low-price laxative without a habit-forming tendency after long-term use, is widely used for treating constipation in Japan. However, its use has been associated with hypermagnesemia in patients with impaired magnesium excretion function such as renal insufficiency. Therefore, in this study, we investigated the use of magnesium oxide tablets, which may be administered to the elderly on a long-term basis. We found the total number of prescriptions has increased year by year and exceeded 4 billion tablets in FY 2020. The use and number of prescriptions were highest among individuals in their 80s, and more than 70% of patients taking the drug are aged 70 years or older. Since the elderly experience physiological functional decline, pharmacists must make effective use of not only age but also laboratory data listed on prescriptions when dispensing these medications in order to prevent adverse events.
Journal
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- Applied Therapeutics
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Applied Therapeutics 18 (0), 16-21, 2023
Japanese Society for Applied Therapeutics
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Details 詳細情報について
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- CRID
- 1390014648121435264
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- ISSN
- 24329185
- 18844278
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- Text Lang
- en
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- Data Source
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- JaLC
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- Abstract License Flag
- Disallowed