CLINICAL EFFICASY OF HOUSE DUST MITE SUBLINGUAL IMMUNOTHERAPY WITH MITICURE<sup>®</sup> TABLETS IN 115 PAITENTS FOR 3 YEARS

DOI

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Other Title
  • ミティキュア<sup>®</sup>錠によるダニ舌下免疫療法115例の3年間治療成績

Abstract

<p>We reported the results of three years of house dust mite sublingual immunotherapy with Miticure® tablets.</p><p>Methods: Subjects of 115 cases (63 males, median 12.9 years old, 74 children under 15 years old) were evaluated with Japanese Rhino-conjunctivitis Quality of Life Questionnaire No1 (JRQLQ No1) and visual analog scale (VAS) of 100mm length for rhino-ocular and general symptoms. Annual survey was conducted for three years.</p><p>Results: Symptoms in all items of 1 to 3 years later by JRQLQ No1 and VAS were significantly improved (p<0.01). There was no difference from 1 year to 3 years later. The VAS value for total symptoms decreased from 41 (18-70) mm before treatment to 10 (4-40) mm after 1 year and 10 (3-30) mm after 3 years (median (IQR)). Concomitant medications used in all patients at the start of treatment were not needed in 60.8% after 1 year and 65.2% after 3 years. After 3 years, 16.5% of the patients were completely cured with no concomitant medication and had a symptom score of 0, and 53.0% were in remission with a score of 1 or less. There was no difference in all items between children and adults, and symptoms improved equally.</p><p>Conclusion: The efficacy of house dust mite sublingual immunotherapy from 1 to 3 years was demonstrated.</p>

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Details 詳細情報について

  • CRID
    1390014713516841088
  • DOI
    10.15036/arerugi.72.273
  • ISSN
    13477935
    00214884
  • Text Lang
    ja
  • Data Source
    • JaLC
  • Abstract License Flag
    Disallowed

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