A case of subacute renal injury with myxoedema coma treated with hemodialysis and successfully weaned from dialysis with thyroid hormone replacement

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  • Nakamura Yurina
    Department of Nephrology, National Hospital Organization Kumamoto Medical Center
  • Kajiwara Kengo
    Department of Nephrology, National Hospital Organization Kumamoto Medical Center
  • Yano Yuko
    Department of Nephrology, National Hospital Organization Kumamoto Medical Center
  • Matsushita Koki
    Department of Nephrology, National Hospital Organization Kumamoto Medical Center
  • Yoshii Ryuichi
    Department of Nephrology, National Hospital Organization Kumamoto Medical Center
  • Nakamura Tomofumi
    Department of Nephrology, National Hospital Organization Kumamoto Medical Center
  • Tomita Masao
    Department of Nephrology, National Hospital Organization Kumamoto Medical Center
  • Kinoshita Hiroyuki
    Department of Diabetes and Endocrinology, National Hospital Organization Kumamoto Medical Center
  • Mukoyama Masashi
    Department of Nephrology, Graduate School of Medical Sciences, Kumamoto University

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Other Title
  • 粘液水腫性昏睡を伴う亜急性腎障害に血液透析を行うも甲状腺ホルモン補充により透析離脱しえた1例
  • ネンエキ スイシュセイ コンスイ オ トモナウ アキュウセイジンショウガイ ニ ケツエキ トウセキ オ オコナウ モ コウジョウセン ホルモン ホジュウ ニ ヨリ トウセキ リダツ シエタ 1レイ

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Abstract

<p>The patient was a 90-year-old woman. She was brought to our hospital for close examination and treatment, including the introduction of dialysis. Renal dysfunction that had worsened from Cre：1.97 to 3.86 mg/dL over a period of 1 year, respiratory distress, and pleural effusion were also observed. After hospitalization and close examination, myxoedema coma was diagnosed, and thyroid hormone replacement was performed along with continuous hemodiafiltration (CHDF). The renal function showed improvement and the patient was transferred to hemodialysis (HD), and could be subsequently weaned off HD. Hypothyroidism is an infrequent cause of renal dysfunction, but prompt intervention has been shown to improve the renal function. When searching for the cause of renal dysfunction, as in the present case, hypothyroidism should be considered, and close examination, including measurement of hormone levels, should be performed.</p>

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