A multi-institutional retrospective study of children and adolescents with hematological cancer who visited oncofertility clinics in the Tokai and Hokuriku regions
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- Takenaka Motoki
- Department of Obstetrics and Gynecology, Gifu University School of Medicine
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- Maezawa Tadashi
- Department of Obstetrics and Gynecology, Mie University School of Medicine
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- Saito Ai
- Department of Obstetrics and Gynecology, Japanese Red Cross Aichi Medical Center Nagoya Daiichi Hospital
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- Bomoto Yoshimasa
- Department of Obstetrics and Gynecology, Gifu University School of Medicine
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- Miyake Natsuki
- Department of Obstetrics and Gynecology, Nagoya University School of Medicine
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- Enomoto Sayako
- Department of Obstetrics and Gynecology, Mie University School of Medicine
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- Nishioka Mikiko
- Department of Obstetrics and Gynecology, Mie University School of Medicine
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- Matsumoto Yosuke
- Department of Obstetrics and Gynecology, Nagoya City University School of Medicine
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- Ito Masami
- Department of Obstetrics and Gynecology, Toyama University School of Medicine
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- Miyazaki Yumiko
- Department of Obstetrics and Gynecology, Fukui University School of Medicine
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- Matsumoto Masako
- Department of Obstetrics and Gynecology, Hamamatsu University School of Medicine
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- Osuka Satoko
- Department of Obstetrics and Gynecology, Nagoya University School of Medicine
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- Goto Maki
- Department of Obstetrics and Gynecology, Nagoya University School of Medicine
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- Ando Tomoko
- Department of Obstetrics and Gynecology, Japanese Red Cross Aichi Medical Center Nagoya Daiichi Hospital
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- Furui Tatsuro
- Department of Obstetrics and Gynecology, Gifu University School of Medicine
Bibliographic Information
- Other Title
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- 東海北陸地方における小児・思春期血液がん患者のがん・生殖相談外来受診状況に対する多機関共同・後ろ向き観察研究
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Abstract
<p>Background: We established a regional oncofertility network in the Tokai and Hokuriku regions started operating it in August 2020. This network aims to optimize care and improve knowledge about oncofertility. We focused on children and adolescents with hematological cancer in this study.</p><p>Methods: This retrospective study was conducted at nine institutions in the Tokai and Hokuriku regions on children and adolescents with hematological cancer. We investigated patients under 18 years of age and diagnosed as having hematological cancer, who visited oncofertility clinics in the nine institutions between January 2013 and June 2021.</p><p>Results: This study included 115 patients (71 males and 44 females) with confirmed hematological cancer. The consultation rate was lower in patients younger than 12 years old. Of the 66 patients who attempted sperm cryopreservation, it was unsuccessful in nine patients because of aspermia. Of the 17 patients who attempted ovarian tissue cryopreservation, the cryopreservation before hematopoietic stem cell transplantation was successful in 16 patients. Seven patients also received a perioperative blood transfusion. Among the 11 patients who attempted oocyte cryopreservation, it was achieved in eight patients, including patients under 14 years of age.</p><p>Conclusion: We expect to support and improve this oncofertility network to explore the need for fertility-preserving procedures on children and adolescents with hematological cancer.</p>
Journal
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- The Japanese Journal of Pediatric Hematology / Oncology
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The Japanese Journal of Pediatric Hematology / Oncology 60 (1), 20-26, 2023
The Japanese Society of Pediatric Hematology / Oncology
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Details 詳細情報について
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- CRID
- 1390014879183415552
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- ISSN
- 21895384
- 2187011X
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- Text Lang
- ja
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- Data Source
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- JaLC
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- Abstract License Flag
- Disallowed