A case report of three laryngeal inflammatory myofibroblastic tumor

DOI Web Site 12 References Open Access
  • Jiromaru Rina
    Department of Otorhinolaryngology, Graduate School of Medical Sciences, Kyushu University
  • Matsuo Mioko
    Department of Otorhinolaryngology, Graduate School of Medical Sciences, Kyushu University
  • Yamamoto Hidetaka
    Department of Anatomic Pathology, Graduate School of Medical Sciences, Kyushu University
  • Kuga Ryosuke
    Department of Otorhinolaryngology, Graduate School of Medical Sciences, Kyushu University Department of Anatomic Pathology, Graduate School of Medical Sciences, Kyushu University
  • Hongo Takahiro
    Department of Otorhinolaryngology, Graduate School of Medical Sciences, Kyushu University Department of Anatomic Pathology, Graduate School of Medical Sciences, Kyushu University
  • Manako Tomomi
    Department of Otorhinolaryngology, Graduate School of Medical Sciences, Kyushu University
  • Hashimoto Kazuki
    Department of Otorhinolaryngology, Graduate School of Medical Sciences, Kyushu University
  • Wakasaki Takahiro
    Department of Otorhinolaryngology, Graduate School of Medical Sciences, Kyushu University
  • Yasumatsu Ryuji
    Department of Otorhinolaryngology Head and Neck Surgery, Faculty of Medicine, Kindai University
  • Nakagawa Takashi
    Department of Otorhinolaryngology, Graduate School of Medical Sciences, Kyushu University

Bibliographic Information

Other Title
  • 喉頭炎症性筋線維芽細胞性腫瘍の3例

Search this article

Description

Inflammatory myofibroblastic tumor （IMT） is a rare intermediate malignant tumor characterized by inflammatory cell infiltration and proliferation of myofibroblastic and fibroblastic spindle cells. In the present study, we experienced three cases of laryngeal IMT. The first case was a 60-year-old man. He underwent laryngomicrosurgery for a right vocal cord tumor, 7mm in size. One year after the surgery, no evidence of recurrence was seen. The second case was a 53-year-old man with a left vocal cord polyp-like lesion 15mm in diameter with a tendency to enlarge. He underwent laryngomicrosurgery. One year after the surgery, no evidence of recurrence was seen. The third case was a 40-year-old man with IMT diagnosed by a biopsy of a subglottic mass. The case was placed on observation and has remained unaffected for four years. Anaplastic lymphoma kinase （ALK） gene rearrangement was confirmed by fluorescence in situ hybridization in all cases. Preoperative diagnosis of IMT is usually difficult because of the lack of characteristic findings. Surgical resection is the first-line treatment. Although it can cause asphyxia, the increase is generally slow and the choice of timing of treatment needs to be tailored to the pathology. IMT usually has a benign course, but cases with local recurrence or distant metastasis have been reported. In laryngeal IMT, local recurrence was reported in about 20％ of cases, and no metastasis was reported. Surgical treatment should be considered in the presence of a hard, enlarging laryngeal mass, with the possibility of IMT.

Journal

References(12)*help

See more

Keywords

Details 詳細情報について

Report a problem

Back to top