A case of otitis media with ANCA-associated vasculitis for which the diagnosis was difficult

DOI
  • MIYAZAKI Mayu
    Department of Otorhinolaryngology, Head and Neck Surgery, Kyushu University Hospital
  • NODA Teppei
    Department of Otorhinolaryngology, Head and Neck Surgery, Kyushu University Hospital
  • AKAGI-TSUCHIHASHI Nana
    Department of Otorhinolaryngology, Head and Neck Surgery, Kyushu University Hospital
  • KOMUNE Noritaka
    Department of Otorhinolaryngology, Head and Neck Surgery, Kyushu University Hospital
  • MATSUMOTO Nozomu
    Department of Otorhinolaryngology, Head and Neck Surgery, Kyushu University Hospital
  • NAKAGAWA Takashi
    Department of Otorhinolaryngology, Head and Neck Surgery, Kyushu University Hospital

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Other Title
  • 診断に苦慮した ANCA 関連血管炎性中耳炎

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Abstract

<p>ANCA-associated vasculitis is an autoimmune vasculitis that often develops in systemic diseases, such as renal disorders and pulmonary lesions. However, there have been increasing reports of ANCA-associated vasculitis of otitis media origin and ear-localized type in recent years. A 52-year-old woman with a history of tuberculosis presented with otitis media refractory to antimicrobial agents as well as hearing loss and headache. Although otitis media with ANCA-associated vasculitis (OMAAV) is mentioned as a differential diagnosis for refractory otitis media, the diagnosis was difficult, as ANCA antibodies were negative, biopsy tissue showed no evidence of vasculitis, and there was concern about the possibility of tuberculous otitis media. We ultimately diagnosed the patient with OMAAV by excluding other diseases thorough a collaborative evaluation of other organs, considering the complication of hypertrophic pachymeningitis, which is characteristic of OMAAV. Since we experienced a case of OMAAV that took one year to be diagnosed, we herein report this diagnosis with some discussion of the literature.</p>

Journal

  • jibi to rinsho

    jibi to rinsho 68 (4), 266-272, 2022-07-20

    JIBI TO RINSHO KAI

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