Autoimmune encephalitis and paraneoplastic neurological syndromes presenting atypical parkinsonism: a scoping review
-
- M.D. Yamahara Naoki
- Department of Neurology, Gifu University Graduate School of Medicine
-
- M.D., Ph.D. Kimura Akio
- Department of Neurology, Gifu University Graduate School of Medicine
-
- M.D., Ph.D Shimohata Takayoshi
- Department of Neurology, Gifu University Graduate School of Medicine
Bibliographic Information
- Other Title
-
- 非定型パーキンソニズムを呈する自己免疫性脳炎/傍腫瘍性神経症候群―スコーピングレビュー―
Abstract
<p>Recent studies have demonstrated that atypical parkinsonism can be presented in autoimmune encephalitis and paraneoplastic neurological syndromes. However, it is unclear which anti-neural antibodies are involved and when these diseases should be suspected. To address these clinical questions, we conducted a scoping review and analyzed 38 articles. The literature shows that many anti-neural antibodies, including unknown ones, have been reported in progressive supranuclear palsy, corticobasal syndrome, and multiple system atrophy. Moreover, the following symptoms and signs suggest the possibility of autoimmune encephalitis and paraneoplastic neurological syndromes: early onset, acute or subacute progression, the presence of a neoplasm, significant weight loss, abnormal cerebrospinal fluid findings, the absence of typical brain magnetic resonance imaging findings, and the existence of atypical physical examination signs.</p>
Journal
-
- Rinsho Shinkeigaku
-
Rinsho Shinkeigaku 63 (8), 497-504, 2023
Societas Neurologica Japonica