Vaginal Cancer Found after Hysterectomy in a Patient with a High-grade Squamous Intraepithelial Lesion: A Case Report

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  • Koguchi Saaya
    Department of Obstetrics and Gynecology, Faculty of Medicine, University of Tsukuba Hospital Department of Obstetrics and Gynecology, Kasumigaura Medical Center
  • Arai Yuko
    Department of Obstetrics and Gynecology, Kasumigaura Medical Center
  • Satoh Toyomi
    Department of Obstetrics and Gynecology, Faculty of Medicine, University of Tsukuba Hospital

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  • 子宮頸部高度扁平上皮内病変による子宮全摘術後に発見された腟癌の１例

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Abstract

<p>Herein, we present a case of vaginal cancer found after hysterectomy in a patient with a high-grade squamous intraepithelial lesion (HSIL). A 62-year-old postmenopausal woman was referred to us with a HSIL. High-risk human papillomavirus type 18 was identified. Eight years passed without abnormal cytology. HSIL was noted again at the age of 70 years, and conization was performed. Histopathological examination of the cervix showed a HSIL, with no lesion on the margin. However, the HSIL persisted on cytology. Therefore, six months later, we performed hysterectomy. Histopathology revealed no evidence of cervical intraepithelial neoplasia 3 in the cervix. One year after the hysterectomy, vaginal cytology showed atypical squamous cells, which led to the pathological diagnosis of vaginal cancer. Radiation therapy was started. This case highlights the importance of paying attention to the possible presence of vaginal cancer in the presence of cytological abnormalities.</p>

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