Hypocortisolemia and Stress-related Disorders : Differential Diagnosis

DOI
  • Matsubayashi Sunao
    Department of Psychosomatic Medicine, Endocrinology and Diabetes Mellitus, Fukuoka Tokushukai Hospital

Bibliographic Information

Other Title
  • 低コルチゾール血症をきたすストレス関連疾患とその鑑別

Abstract

<p>Background : The physical symptoms of stress-related diseases with hypocortisolemia are similar to those of a typical physical disorder of adrenal insufficiency (e.g., fatigue, anorexia, weight loss, excessive sleepiness, nausea, diarrhea, joint pain, muscle pain, dizziness, and low-grade fever).</p><p>Methods and results : Patients presenting at a psychosomatic clinic with prolonged fatigue were examined using a diagnostic algorithm for adrenal insufficiency. One-fifth of patients were diagnosed with central adrenal insufficiency. Two-thirds of these patients had depression, 1/3 had experienced trauma, and 2/5 had a history of exogenous steroid use due to pre-existing conditions, such as bronchial asthma.</p><p>Conclusion : In the treatment of stress-related disorders associated with hypocortisolemia, it is necessary to be aware of physical comorbidities, such as autoimmune and allergic diseases and a history of exogenous steroid use, and to keep in mind the differentiation of central adrenal insufficiency.</p>

Journal

Keywords

Details 詳細情報について

  • CRID
    1390015830352583936
  • DOI
    10.15064/jjpm.63.5_409
  • ISSN
    21895996
    03850307
  • Text Lang
    ja
  • Data Source
    • JaLC
  • Abstract License Flag
    Disallowed

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