魚類をモデルとした高用量アスコルビン酸投与による酸化ストレス軽減評価

DOI 機関リポジトリ Web Site

書誌事項

タイトル別名
  • ギョルイ オ モデル ト シタ コウヨウリョウ アスコルビンサン トウヨ ニ ヨル サンカ ストレス ケイゲン ヒョウカ

この論文をさがす

抄録

High-dose administration of ascorbic acid is expected to be beneficial for various diseases, but the mechanism is still unclear. In the present study, we investigated the effects of ascorbic acid administration on oxidative stress in a fish model. As a result, there were no differences between administration and control groups, except for a significant decrease in the CAT activity in hepatopancreas. On the other hand, lipid peroxide levels in all tissues were lower compared with control group, suggesting that this experimental system can be used as a model for high-dose ascorbic acid administration. In the future, it will be necessary to optimize the concentration, frequency, and duration of administration, and analyze the effects of the administration on the antioxidant defense capacity of each tissue throughout experimental period to conclude the usefulness of this administration model.

収録刊行物

キーワード

詳細情報 詳細情報について

問題の指摘

ページトップへ