Pulsed Field Ablation-Based Pulmonary Vein Isolation Using a Simplified Single-Access Single-Catheter Approach ― The Fast and Furious PFA Study ―
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- Tilz Roland R.
- Department of Rhythmology, University Heart Center Lübeck, University Hospital Schleswig-Holstein German Center for Cardiovascular Research (DZHK), Partner Site Hamburg/Kiel/Lübeck
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- Vogler Julia
- Department of Rhythmology, University Heart Center Lübeck, University Hospital Schleswig-Holstein
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- Kirstein Bettina
- Department of Rhythmology, University Heart Center Lübeck, University Hospital Schleswig-Holstein
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- Eitel Charlotte
- Department of Rhythmology, University Heart Center Lübeck, University Hospital Schleswig-Holstein
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- Phan Huong-Lan
- Department of Rhythmology, University Heart Center Lübeck, University Hospital Schleswig-Holstein
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- Popescu Sorin Ștefan
- Department of Rhythmology, University Heart Center Lübeck, University Hospital Schleswig-Holstein
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- Hatahet Sascha
- Department of Rhythmology, University Heart Center Lübeck, University Hospital Schleswig-Holstein
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- Große Niels
- Department of Rhythmology, University Heart Center Lübeck, University Hospital Schleswig-Holstein
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- Subin Behnam
- Department of Rhythmology, University Heart Center Lübeck, University Hospital Schleswig-Holstein
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- Lopez Lisbeth Delgado
- Department of Rhythmology, University Heart Center Lübeck, University Hospital Schleswig-Holstein
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- Kuck Karl-Heinz
- Department of Rhythmology, University Heart Center Lübeck, University Hospital Schleswig-Holstein
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- Heeger Christian-H.
- Department of Rhythmology, University Heart Center Lübeck, University Hospital Schleswig-Holstein German Center for Cardiovascular Research (DZHK), Partner Site Hamburg/Kiel/Lübeck
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説明
<p>Background: Pulsed field ablation (PFA) is a non-thermal energy source with promising safety and efficacy advantages. We aimed to develop a convenient, safe, effective and fast method of pulmonary vein isolation (PVI) utilizing a penta-spline PFA catheter via a single femoral vein and a venous closure system.</p><p>Methods and Results: Consecutive patients (n=50; mean age: 63.6±10.7 years, 38% female) presenting with AF (paroxysmal AF: 56%) underwent first-time PVI via PFA. A single ultrasound-guided femoral vein puncture and a single transseptal puncture were used. After PVI using the penta-spline PFA catheter, extra pulse trains were added to the posterior wall for wide antral circumferential ablation. A venous closure system was used and a Donati suture was performed. The pressure bandage was removed after 1 h. A total of 196 PVs were identified and isolated with PFA only. The mean procedural time was 27.4±6.6 min, and the mean dwelling time was 14.4±5.5 min. Time to ambulation was 3.3±3.1 h. No severe complications occurred. During a mean follow-up of 6.5±2.1 months, 41/50 patients (82%) remained in sinus rhythm.</p><p>Conclusions: The combination of a single venous puncture, single transseptal puncture approach using PFA and vascular closure device resulted in a 100% rate of acute PVI and an extraordinarily fast procedure and time to ambulation. The rate of periprocedural complications was low.</p>
収録刊行物
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- Circulation Journal
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Circulation Journal 87 (12), 1722-1726, 2023-11-24
一般社団法人 日本循環器学会
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詳細情報 詳細情報について
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- CRID
- 1390016759113512064
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- NII書誌ID
- AA11591968
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- ISSN
- 13474820
- 13469843
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- NDL書誌ID
- 033193509
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- PubMed
- 37532529
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- 本文言語コード
- en
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- データソース種別
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- JaLC
- NDL
- Crossref
- PubMed
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- 使用不可