Carbonate apatite versus β-tricalcium phosphate for rat vertical bone augmentation: A comparison of bioresorbable bone substitutes using polytetrafluoroethylene tubes
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- YANO Makiko
- Department of Orthodontics, Osaka Dental University
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- YASUI Kenichirou
- Department of Orthodontics, Osaka Dental University
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- JO Jun-ichiro
- Department of Biomaterials, Osaka Dental University
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- NISHIURA Aki
- Department of Orthodontics, Osaka Dental University
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- HASHIMOTO Yoshiya
- Department of Biomaterials, Osaka Dental University
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- MATSUMOTO Naoyuki
- Department of Orthodontics, Osaka Dental University
抄録
<p>This study radiologically and histologically compared two bioresorbable bone substitutes with different compositions carbonate apatite (Cytrans® Granules; CGs) and β-tricalcium phosphate (β-TCP) for vertical bone augmentation on a rat skull using a polytetrafluoroethylene (PTFE) tubes. This PTFE tube was placed at the center of the skull, fixed with Super Bond, and augmented with CGs or β-TCP granules. Specimens with surrounding tissue were harvested at 4, 8, and 12 weeks postoperatively, and radiological and histological evaluations were performed. The bone volume to total volume ratio (BV/TV) of the β-TCP-implanted group was markedly higher than that of the CG-implanted group at 4 and 12 weeks postoperatively. Compared to CGs, β-TCP exhibited the ability to form blood vessels into the graft material for a short period after transplantation, as well as an elevated production of collagen into β-TCP granules during the bone formation process.</p>
収録刊行物
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- Dental Materials Journal
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Dental Materials Journal 42 (6), 851-859, 2023-11-25
一般社団法人 日本歯科理工学会