Two Cases of Granulomatous Mastitis with Erythema Nodosum

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  • 結節性紅斑を併発した肉芽腫性乳腺炎の2例
  • ケッセツセイコウ ハン オ ヘイハツ シタ ニクゲシュセイ ニュウセンエン ノ 2レイ

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Abstract

<p>Two cases of granulomatous mastitis with erythema nodosum are reported.</p><p>Case 1 : A 32-year-old woman presented with a painful right breast mass. Antibiotic treatment was ineffective. She was diagnosed as having granulomatous mastitis based on the clinical course. Painful erythema on her lower legs, joint pain, and high fever appeared 24 days after onset. A drug eruption was suspected, but her symptoms did not improve with antibiotic discontinuation. The skin biopsy showed erythema nodosum. The erythema nodosum resolved spontaneously, while the granulomatous mastitis worsened. After she was treated with steroids and drainage, the granulomatous mastitis improved.</p><p>Case 2 : A 38-year-old woman presented with a painful left breast mass. Antibiotic treatment was ineffective. The diagnosis on breast biopsy was granulomatous mastitis. Painful erythema appeared on her lower leg 22 days after onset. She was diagnosed with erythema nodosum based on her clinical findings. She followed the same course as case 1, and her granulomatous mastitis improved only with drainage.</p><p>Erythema nodosum should be considered when painful erythema appears in patients with granulomatous mastitis.</p>

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