-
- Harada Sei
- Department of Preventive Medicine and Public Health, Keio University School of Medicine Institute for Advanced Biosciences, Keio University
-
- Iida Miho
- Department of Preventive Medicine and Public Health, Keio University School of Medicine Institute for Advanced Biosciences, Keio University
-
- Miyagawa Naoko
- Department of Preventive Medicine and Public Health, Keio University School of Medicine
-
- Hirata Aya
- Department of Preventive Medicine and Public Health, Keio University School of Medicine
-
- Kuwabara Kazuyo
- Department of Preventive Medicine and Public Health, Keio University School of Medicine
-
- Matsumoto Minako
- Department of Preventive Medicine and Public Health, Keio University School of Medicine
-
- Okamura Tomonori
- Department of Preventive Medicine and Public Health, Keio University School of Medicine
-
- Edagawa Shun
- Department of Preventive Medicine and Public Health, Keio University School of Medicine
-
- Kawada Yoko
- Department of Preventive Medicine and Public Health, Keio University School of Medicine
-
- Miyake Atsuko
- Department of Obstetrics and Gynecology, Keio University School of Medicine
-
- Toki Ryota
- Department of Preventive Medicine and Public Health, Keio University School of Medicine
-
- Akiyama Miki
- Institute for Advanced Biosciences, Keio University Faculty of Environment and Information Studies, Keio University
-
- Kawai Atsuki
- Institute for Advanced Biosciences, Keio University
-
- Sugiyama Daisuke
- Faculty of Nursing and Medical Care and Graduate School of Health Management, Keio University
-
- Sato Yasunori
- Department of Preventive Medicine and Public Health, Keio University School of Medicine Biostatistics Unit, Clinical and Translational Research Center, Keio University Hospital
-
- Takemura Ryo
- Biostatistics Unit, Clinical and Translational Research Center, Keio University Hospital
-
- Fukai Kota
- Department of Preventive Medicine and Public Health, Keio University School of Medicine
-
- Ishibashi Yoshiki
- Department of Preventive Medicine and Public Health, Keio University School of Medicine
-
- Kato Suzuka
- Department of Preventive Medicine and Public Health, Keio University School of Medicine
-
- Kurihara Ayako
- Department of Preventive Medicine and Public Health, Keio University School of Medicine
-
- Sata Mizuki
- Department of Preventive Medicine and Public Health, Keio University School of Medicine
-
- Shibuki Takuma
- Department of Preventive Medicine and Public Health, Keio University School of Medicine
-
- Takeuchi Ayano
- Department of Preventive Medicine and Public Health, Keio University School of Medicine
-
- Kohsaka Shun
- Department of Cardiology, Keio University School of Medicine
-
- Sawano Mitsuaki
- Department of Cardiology, Keio University School of Medicine
-
- Shoji Satoshi
- Department of Cardiology, Keio University School of Medicine Duke Clinical Research Institute
-
- Izawa Yoshikane
- Department of Neurology, Keio University School of Medicine
-
- Katsumata Masahiro
- Department of Neurology, Keio University School of Medicine
-
- Oki Koichi
- Department of Neurology, Keio University School of Medicine Department of Neurology, Tokyo Saiseikai Central Hospital
-
- Takahashi Shinichi
- Department of Neurology, Keio University School of Medicine Department of Neurology and Stroke, Saitama Medical University International Medical Center
-
- Takizawa Tsubasa
- Department of Neurology, Keio University School of Medicine
-
- Maruya Hiroshi
- Shonai Hospital
-
- Nishiwaki Yuji
- Department of Environmental and Occupational Health, School of Medicine, Toho University
-
- Kawasaki Ryo
- Division of Public Health, Department of Social Medicine, Graduate School of Medicine, Osaka University
-
- Hirayama Akiyoshi
- Institute for Advanced Biosciences, Keio University
-
- Ishikawa Takamasa
- Institute for Advanced Biosciences, Keio University
-
- Saito Rintaro
- Institute for Advanced Biosciences, Keio University
-
- Sato Asako
- Institute for Advanced Biosciences, Keio University
-
- Soga Tomoyoshi
- Institute for Advanced Biosciences, Keio University
-
- Sugimoto Masahiro
- Institute for Advanced Biosciences, Keio University
-
- Tomita Masaru
- Institute for Advanced Biosciences, Keio University
-
- Komaki Shohei
- Division of Biomedical Information Analysis, Institute for Biomedical Sciences of Iwate Medical University Division of Biomedical Information Analysis, Iwate Tohoku Medical Megabank Organization, Disaster Reconstruction Center, Iwate Medical University
-
- Ohmomo Hideki
- Division of Biomedical Information Analysis, Institute for Biomedical Sciences of Iwate Medical University Division of Biomedical Information Analysis, Iwate Tohoku Medical Megabank Organization, Disaster Reconstruction Center, Iwate Medical University
-
- Ono Kanako
- Department of Preventive Medicine and Public Health, Keio University School of Medicine Division of Biomedical Information Analysis, Iwate Tohoku Medical Megabank Organization, Disaster Reconstruction Center, Iwate Medical University
-
- Otsuka-Yamasaki Yayoi
- Division of Biomedical Information Analysis, Institute for Biomedical Sciences of Iwate Medical University Division of Biomedical Information Analysis, Iwate Tohoku Medical Megabank Organization, Disaster Reconstruction Center, Iwate Medical University
-
- Shimizu Atsushi
- Department of Preventive Medicine and Public Health, Keio University School of Medicine Division of Biomedical Information Analysis, Institute for Biomedical Sciences of Iwate Medical University Division of Biomedical Information Analysis, Iwate Tohoku Medical Megabank Organization, Disaster Reconstruction Center, Iwate Medical University
-
- Sutoh Yoichi
- Division of Biomedical Information Analysis, Institute for Biomedical Sciences of Iwate Medical University Division of Biomedical Information Analysis, Iwate Tohoku Medical Megabank Organization, Disaster Reconstruction Center, Iwate Medical University
-
- Hozawa Atsushi
- Tohoku Medical Megabank Organization, Tohoku University Graduate School of Medicine, Tohoku University
-
- Kinoshita Kengo
- Tohoku Medical Megabank Organization, Tohoku University Graduate School of Information Sciences, Tohoku University Advanced Research Center for Innovations in Next-Generation Medicine, Tohoku University Institute of Development, Aging and Cancer, Tohoku University
-
- Koshiba Seizo
- Tohoku Medical Megabank Organization, Tohoku University
-
- Kumada Kazuki
- Tohoku Medical Megabank Organization, Tohoku University
-
- Ogishima Soichi
- Tohoku Medical Megabank Organization, Tohoku University
-
- Sakurai-Yageta Mika
- Tohoku Medical Megabank Organization, Tohoku University
-
- Tamiya Gen
- Tohoku Medical Megabank Organization, Tohoku University Graduate School of Medicine, Tohoku University Center for Advanced Intelligence Project, RIKEN
-
- Takebayashi Toru
- Department of Preventive Medicine and Public Health, Keio University School of Medicine Institute for Advanced Biosciences, Keio University
抄録
<p>The Tsuruoka Metabolomics Cohort Study (TMCS) is an ongoing population-based cohort study being conducted in the rural area of Yamagata Prefecture, Japan. This study aimed to enhance the precision prevention of multi-factorial, complex diseases, including non-communicable and aging-associated diseases, by improving risk stratification and prediction measures. At baseline, 11,002 participants aged 35–74 years were recruited in Tsuruoka City, Yamagata Prefecture, Japan, between 2012 and 2015, with an ongoing follow-up survey. Participants underwent various measurements, examinations, tests, and questionnaires on their health, lifestyle, and social factors. This study used an integrative approach with deep molecular profiling to identify potential biomarkers linked to phenotypes that underpin disease pathophysiology and provide better mechanistic insights into social health determinants. The TMCS incorporates multi-omics data, including genetic and metabolomic analyses of 10,933 participants and comprehensive data collection ranging from physical, psychological, behavioral, and social to biological data. The metabolome is used as a phenotypic probe because it is sensitive to changes in physiological and external conditions. The TMCS focuses on collecting outcomes for cardiovascular disease, cancer incidence and mortality, disability, functional decline due to aging and disease sequelae, and the variation in health status within the body represented by omics analysis that lies between exposure and disease. It contains several sub-studies on aging, heated tobacco products, and women's health. This study is notable for its robust design, high participation rate (89%), and long-term repeated surveys. Moreover, it contributes to precision prevention in Japan and East Asia as a well-established multi-omics platform.</p>
収録刊行物
-
- Journal of Epidemiology
-
Journal of Epidemiology advpub (0), 2024
日本疫学会
- Tweet
詳細情報 詳細情報について
-
- CRID
- 1390017267761789440
-
- ISSN
- 13499092
- 09175040
-
- 本文言語コード
- en
-
- データソース種別
-
- JaLC
- Crossref
-
- 抄録ライセンスフラグ
- 使用不可