Clinical analysis of cases of pT4 parotid gland cancer
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- Sato Fumihiko
- Department of Otolaryngology-Head and Neck Surgery, Kurume University School of Medicine
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- Ono Takeharu
- Department of Otolaryngology-Head and Neck Surgery, Kurume University School of Medicine
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- Sato Kiminobu
- Department of Otolaryngology-Head and Neck Surgery, Kurume University School of Medicine
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- Mitsuhashi Toshiyuki
- Department of Otolaryngology-Head and Neck Surgery, Kurume University School of Medicine
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- Chitose Shun-ichi
- Department of Otolaryngology-Head and Neck Surgery, Kurume University School of Medicine
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- Umeno Hirohito
- Department of Otolaryngology-Head and Neck Surgery, Kurume University School of Medicine
Bibliographic Information
- Other Title
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- 耳下腺癌pT4症例の検討
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Abstract
In cases of T4 parotid carcinoma requiring extended resection, sacrificing the facial nerve can reduce quality of life. In this study, we examined 25 patients with pT4 parotid carcinoma who underwent radical surgery at our department. The cohort comprised 17 men and 8 women, with patients’ age ranging from 8 to 81 years, and the median observation period being 8.6 years. Overall, 16 patients had high-grade disease. Of the 14 patients without preoperative facial nerve palsy, 6 had high-grade disease, and facial nerve preservation was achieved in 2 of them. The 5-year locoregional control rate was 74.4%, 5-year distant metastasis rate was 45.4%, and overall 5-year survival rate was 59.5%. Univariate analysis showed that only the pathological grade was a prognostic factor for locoregional control, distant metastasis, and overall survival. For patients with T4 parotid carcinoma without preoperative facial nerve palsy, our results suggest that sacrificing the facial nerve does not improve outcomes, although it is common in high-grade cases.
Journal
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- Toukeibu Gan
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Toukeibu Gan 49 (4), 299-304, 2023
Japan Society for Head and Neck Cancer
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Details 詳細情報について
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- CRID
- 1390017511236307840
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- ISSN
- 18818382
- 13495747
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- Text Lang
- ja
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- Data Source
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- JaLC
- Crossref
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- Abstract License Flag
- Disallowed