Outcomes of Endovascular Treatment for Infective Aortic Aneurysms ― A Multicenter Retrospective Study ―
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- Lee Chih-Chun
- Department of Medical Education, Chang Gung Memorial Hospital
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- Chen Dong-Yi
- Department of Cardiology, Chang Gung Memorial Hospital, Chang Gung University
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- Chan Yi-Hsin
- Department of Cardiology, Chang Gung Memorial Hospital, Chang Gung University
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- Wu Victor Chien-Chia
- Department of Cardiology, Chang Gung Memorial Hospital, Chang Gung University
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- Cheng Yu-Ting
- Division of Thoracic and Cardiovascular Surgery, Department of Surgery, Chang Gung Memorial Hospital, Chang Gung University
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- Hung Kuo-Chun
- Department of Cardiology, Chang Gung Memorial Hospital, Chang Gung University
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- Lin Chia-Pin
- Department of Cardiology, Chang Gung Memorial Hospital, Chang Gung University
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- Tung Ying-Chang
- Department of Cardiology, Chang Gung Memorial Hospital, Chang Gung University
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- Hsiao Fu-Chih
- Department of Cardiology, Chang Gung Memorial Hospital, Chang Gung University
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- Yeh Jih-Kai
- Department of Cardiology, Chang Gung Memorial Hospital, Chang Gung University
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- Chu Pao-Hsien
- Department of Cardiology, Chang Gung Memorial Hospital, Chang Gung University
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- Chen Shao-Wei
- Division of Thoracic and Cardiovascular Surgery, Department of Surgery, Chang Gung Memorial Hospital, Chang Gung University Center for Big Data Analytics and Statistics, Chang Gung Memorial Hospital
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<p>Background: In Taiwan, infective native aortic aneurysms (INAAs) are relatively common, so the aim of present study was to demonstrate the comparative outcomes of endovascular repair for thoracic and abdominal INAAs.</p><p>Methods and Results: Patients with naïve thoracic or abdominal INAAs managed with endovascular repair between 2001 and 2018 were included in this multicenter retrospective cohort. The confounding factors were adjusted with propensity score (PS). Of the 39 thoracic and 43 abdominal INAA cases, 41 (50%) presented with aneurysmal rupture, most of which were at the infrarenal abdominal (n=35, 42.7%) or descending thoracic aorta (n=25, 30.5%). Salmonella spp. was the most frequently isolated pathogen. The overall in-hospital mortality rate was 18.3%. The risks of in-hospital death and death due to rupture were significantly lower with thoracic INAAs (12.8% vs. 23.3%; PS-adjusted odds ratio (OR) 0.24, 95% confidence interval (CI) 0.06–0.96; 0.1% vs. 9.3%; PS-adjusted OR 0.11, 95% CI 0.01–0.90). During a mean follow-up of 2.5 years, the risk of all-cause death was significantly higher with thoracic INAAs (35.3% vs. 15.2%; PS-adjusted HR 6.90, 95% CI 1.69–28.19). Chronic kidney disease (CKD) was associated with death.</p><p>Conclusions: Compared with thoracic INAAs, endovascular repair of abdominal INAAs was associated with a significantly higher in-hospital mortality rate. However, long-term outcomes were worse for thoracic INAAs, with CKD and infections being the most important predictor and cause of death, respectively.</p>
収録刊行物
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- Circulation Journal
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Circulation Journal 88 (3), 309-318, 2024-02-22
一般社団法人 日本循環器学会
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詳細情報 詳細情報について
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- CRID
- 1390017754378678016
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- NII書誌ID
- AA11591968
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- ISSN
- 13474820
- 13469843
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- NDL書誌ID
- 033364353
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- PubMed
- 37648519
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- 本文言語コード
- en
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- データソース種別
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- JaLC
- NDL
- Crossref
- PubMed
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- 抄録ライセンスフラグ
- 使用不可