The gender-related difference for decision-making on non-invasive prenatal testing (NIPT) for fetal chromosomal aberration.

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  • Ishimatsu Aki
    Perinatal Medical Center, Kumamoto University Hospital
  • Nakamura Erika
    Perinatal Medical Center, Kumamoto University Hospital
  • Tominaga Rumiko
    Perinatal Medical Center, Kumamoto University Hospital
  • Ushijima Terumi
    Perinatal Medical Center, Kumamoto University Hospital
  • Taura Yumiko
    Department of Obstetrics and Gynecology Faculty of Life Sciences, Kumamoto University
  • Sasaki Rumi
    Department of Obstetrics and Gynecology Faculty of Life Sciences, Kumamoto University
  • Ohba Takashi
    Department of Obstetrics and Gynecology Faculty of Life Sciences, Kumamoto University

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Other Title
  • 胎児染色体数的異常に対する無侵襲的遺伝学的検査（NIPT）のカウンセリングを受ける男女（夫婦）の意思決定に関わる意識の相違について
  • タイジ センショクタイスウテキ イジョウ ニ タイスル ムシンシュウテキ イデンガクテキ ケンサ(NIPT)ノ カウンセリング オ ウケル ダンジョ(フウフ)ノ イシ ケッテイ ニ カカワル イシキ ノ ソウイ ニ ツイテ

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Abstract

<p>　The concern and the decision-making process for prenatal diagnosis are presumed to be different between couples. Here we perform this research to understand the characteristics of each couple who wished to undergo noninvasive prenatal testing (NIPT) for fetal chromosomal aberration. Men and women who agreed to participate with this research were subjected among the 90 couples who visited to A University Hospital for NIPT from December 2015 to June 2016. The Age, information sources of NIPT, reliance on the partner, and intention before counseling were examined from the interview questionnaire retrospectively. There were 142 effective respondents (79 wives and 63 husbands). The average age at the expected day of confinement was 39.1 years for wife and 40.9 years for husband. Thirty-four (43.0%) were conceived while receiving infertility treatments. The most common (92.4%) reason for the subjects selecting NIPT was “elderly pregnancy”.</p><p>　Magazines and the internet were the main source of information for both, whereas not the wives but the husbands mainly obtained the information from their partners. Wives were more willing than husbands to receive NIPT, and women who chose NIPT had stronger intention to examine before counseling. Though there was no difference in female age for the decision-making for NIPT, the husband of the couples who did not choose NIPT were older, and older than their wife. In conclusion, decision making for NIPT was primarily prepared and led by the wife, and the fact that the husband is older may be related to suppressive influence for the decision-making of NIPT.</p>

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