The Impact of Gd-EOB-DTPA Contrast-enhanced MR Imaging on the Diagnosis of Benign Neoplastic and Non-neoplastic Liver Lesions

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  • Gd-EOB-DTPA造影MRIによる肝良性腫瘍，非腫瘍性病変の画像診断

Abstract

<p>　Gadolinium ethoxybenzyl-diethylenetriaminepentaacetic acid is a hepatobiliary-specific contrast agent used for enhanced magnetic resonance imaging (EOB-MRI). It can provide specific information on hepatobiliary phase images. In addition to dynamic contrast studies, it is excellent for the detection and characterization of liver lesions.</p><p>　Various benign neoplastic and non-non-neoplastic liver lesions have been reported. Among them, benign hepatocellular nodules, including focal nodular hyperplasia (FNH), FNH-like lesions, and hepatocellular adenoma with β-catenin mutation, can be characterized as hyperintensity in hepatobiliary phase images. Arterio-portal shunts can be accurately diagnosed by being detected in hepatobiliary phase images. In addition to focal nodular lesions, EOB-MRI has affected the diagnosis and detection of impaired sinusoidal perfusion disorders, such as sinusoidal obstruction syndrome and porto-sinusoidal vascular disorder. The distinctive features of EOB-MRI have made it indispensable for the diagnosis of benign neoplastic and non-neoplastic liver lesions in clinical settings over the past 15 years.</p>

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