Limb Salvage Surgery for Ponatinib-Induced Bilateral Chronic Limb-Threatening Ischemia in a Patient with Chronic Myeloid Leukemia with T315I Mutation in BCR-ABL: A Case Report
-
- Nomura Takuo
- Department of Vascular Surgery, Juzen Memorial Hospital, Hamamatsu, Shizuoka, Japan
-
- Hata Akito
- Division of Thoracic Oncology, Kobe Minimally Invasive Cancer Center, Kobe, Hyogo, Japan
説明
<p>A 72-year-old woman with chronic myeloid leukemia with T315I mutation in breakpoint cluster region-abelson (BCR-ABL) was treated with ponatinib. During the course of her treatment, chronic limb-threatening ischemia developed in both lower extremities, and the left lower extremity was amputated below the knee at a previous hospital. She was referred to our department for salvage of the right lower extremity. We performed a foot bypass and multidisciplinary treatment of the wound, and achieved epithelialization in about 1 month. The rate of vascular occlusive events with ponatinib has been reported to be high, and we believe that careful monitoring is important during use.</p>
収録刊行物
-
- Annals of Vascular Diseases
-
Annals of Vascular Diseases 17 (1), 51-54, 2024
Annals of Vascular Diseases 編集委員会
- Tweet
詳細情報 詳細情報について
-
- CRID
- 1390018120873440256
-
- ISSN
- 18816428
- 1881641X
-
- 本文言語コード
- en
-
- データソース種別
-
- JaLC
- Crossref
-
- 抄録ライセンスフラグ
- 使用不可