Two-Year Clinical Outcome of MitraClip Transcatheter Edge-to-Edge Repair From the J-MITRA Registry Data

DOI Web Site Web Site PubMed 参考文献24件
  • Imamura Teruhiko
    Second Department of Internal Medicine, University of Toyama
  • Nakai Michikazu
    Department of Medical and Health Information Management, National Cerebral and Cardiovascular Center Clinical Research Support Center, University of Miyazaki Hospital
  • Iwanaga Yoshitaka
    Department of Medical and Health Information Management, National Cerebral and Cardiovascular Center Department of Cardiology, Sakurabashi-Watanabe Hospital
  • Sumita Yoko
    Department of Medical and Health Information Management, National Cerebral and Cardiovascular Center
  • Tao Misato
    Department of Medical and Health Information Management, National Cerebral and Cardiovascular Center
  • Ohno Yohei
    Division of Cardiology, Department of Internal Medicine, Tokai University School of Medicine
  • Hayashida Kentaro
    Department of Cardiology, Keio University School of Medicine
  • Morino Yoshihiro
    Division of Cardiology, Department of Internal Medicine, Iwate Medical University
  • Seo Yoshihiro
    Department of Cardiology, Nagoya City University Graduate School of Medical Sciences
  • Saiki Yoshikatsu
    Division of Cardiovascular Surgery, Tohoku University Graduate School of Medicine
  • Anzai Toshihisa
    Department of Cardiovascular Medicine, Faculty of Medicine and Graduate School of Medicine, Hokkaido University
  • Toda Koichi
    Department of Cardiovascular Surgery, Dokkyo Medical University Saitama Medical Center
  • Matsumiya Goro
    Department of Cardiovascular Surgery, Chiba University Graduate School of Medicine
  • Yamamoto Kazuhiro
    Division of Cardiovascular Medicine and Endocrinology and Metabolism, Faculty of Medicine, Tottori University
  • Hirata Kenichi
    Division of Cardiovascular Medicine, Department of Internal Medicine, Kobe University Graduate School of Medicine
  • Kinugawa Koichiro
    Second Department of Internal Medicine, University of Toyama
  • on behalf of J-MITRA Investigators

この論文をさがす

抄録

<p>Background: The introduction of transcatheter edge-to-edge repair for moderate-to-severe or severe mitral regurgitation (MR) utilizing the MitraClip system became reimbursed and clinically accessible in Japan in April 2018. This study presents the 2-year clinical outcomes of all consecutively treated patients who underwent MitraClip implantation in Japan and were prospectively enrolled in the Japanese Circulation Society-oriented J-MITRA registry.</p><p>Methods and Results: Analysis encompassed 2,739 consecutive patients enrolled in the J-MITRA registry with informed consent (mean age: 78.3±9.6 years, 1,550 males, STS risk score 11.7±8.9), comprising 1,999 cases of functional MR, 644 of degenerative MR and 96 in a mixed group (DMR and FMR). The acute procedure success rate was 88.9%. After MitraClip implantation, >80% exhibited an MR grade ≤2+ and the trend was sustained over the 2 years. Within this observation period, the mortality rate was 19.3% and the rate of heart failure readmissions was 20.6%. The primary composite endpoint, inclusive of cardiovascular death and heart failure readmission, was significantly higher in patients with functional MR than in with degenerative MR (32.0% vs. 17.5%, P<0.001).</p><p>Conclusions: The 2-year clinical outcomes after MitraClip implantation were deduced from comprehensive data within an all-Japan registry.</p>

収録刊行物

  • Circulation Journal

    Circulation Journal 88 (4), 539-548, 2024-03-25

    一般社団法人 日本循環器学会

参考文献 (24)*注記

もっと見る

キーワード

詳細情報 詳細情報について

問題の指摘

ページトップへ