Two-Year Clinical Outcome of MitraClip Transcatheter Edge-to-Edge Repair From the J-MITRA Registry Data
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- Imamura Teruhiko
- Second Department of Internal Medicine, University of Toyama
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- Nakai Michikazu
- Department of Medical and Health Information Management, National Cerebral and Cardiovascular Center Clinical Research Support Center, University of Miyazaki Hospital
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- Iwanaga Yoshitaka
- Department of Medical and Health Information Management, National Cerebral and Cardiovascular Center Department of Cardiology, Sakurabashi-Watanabe Hospital
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- Sumita Yoko
- Department of Medical and Health Information Management, National Cerebral and Cardiovascular Center
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- Tao Misato
- Department of Medical and Health Information Management, National Cerebral and Cardiovascular Center
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- Ohno Yohei
- Division of Cardiology, Department of Internal Medicine, Tokai University School of Medicine
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- Hayashida Kentaro
- Department of Cardiology, Keio University School of Medicine
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- Morino Yoshihiro
- Division of Cardiology, Department of Internal Medicine, Iwate Medical University
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- Seo Yoshihiro
- Department of Cardiology, Nagoya City University Graduate School of Medical Sciences
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- Saiki Yoshikatsu
- Division of Cardiovascular Surgery, Tohoku University Graduate School of Medicine
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- Anzai Toshihisa
- Department of Cardiovascular Medicine, Faculty of Medicine and Graduate School of Medicine, Hokkaido University
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- Toda Koichi
- Department of Cardiovascular Surgery, Dokkyo Medical University Saitama Medical Center
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- Matsumiya Goro
- Department of Cardiovascular Surgery, Chiba University Graduate School of Medicine
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- Yamamoto Kazuhiro
- Division of Cardiovascular Medicine and Endocrinology and Metabolism, Faculty of Medicine, Tottori University
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- Hirata Kenichi
- Division of Cardiovascular Medicine, Department of Internal Medicine, Kobe University Graduate School of Medicine
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- Kinugawa Koichiro
- Second Department of Internal Medicine, University of Toyama
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説明
<p>Background: The introduction of transcatheter edge-to-edge repair for moderate-to-severe or severe mitral regurgitation (MR) utilizing the MitraClip system became reimbursed and clinically accessible in Japan in April 2018. This study presents the 2-year clinical outcomes of all consecutively treated patients who underwent MitraClip implantation in Japan and were prospectively enrolled in the Japanese Circulation Society-oriented J-MITRA registry.</p><p>Methods and Results: Analysis encompassed 2,739 consecutive patients enrolled in the J-MITRA registry with informed consent (mean age: 78.3±9.6 years, 1,550 males, STS risk score 11.7±8.9), comprising 1,999 cases of functional MR, 644 of degenerative MR and 96 in a mixed group (DMR and FMR). The acute procedure success rate was 88.9%. After MitraClip implantation, >80% exhibited an MR grade ≤2+ and the trend was sustained over the 2 years. Within this observation period, the mortality rate was 19.3% and the rate of heart failure readmissions was 20.6%. The primary composite endpoint, inclusive of cardiovascular death and heart failure readmission, was significantly higher in patients with functional MR than in with degenerative MR (32.0% vs. 17.5%, P<0.001).</p><p>Conclusions: The 2-year clinical outcomes after MitraClip implantation were deduced from comprehensive data within an all-Japan registry.</p>
収録刊行物
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- Circulation Journal
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Circulation Journal 88 (4), 539-548, 2024-03-25
一般社団法人 日本循環器学会
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詳細情報 詳細情報について
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- CRID
- 1390018120873469184
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- NII書誌ID
- AA11591968
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- ISSN
- 13474820
- 13469843
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- NDL書誌ID
- 033409766
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- PubMed
- 38447968
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- 本文言語コード
- en
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- データソース種別
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- JaLC
- NDL
- Crossref
- PubMed
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- 抄録ライセンスフラグ
- 使用不可