Recent Changes in Intervention for Delirium and Biological Background

DOI
  • Hatta Kotaro
    Juntendo University Graduate School of Medicine, Department of Psychiatry and Behavioral Sciences Juntendo University School of Medicine, Nerima Hospital

Bibliographic Information

Other Title
  • 展望：せん妄の介入法における近年の変化と生物学的背景

Abstract

Non‐pharmacologic interventions have taken the lead in terms of the level of evidence for intervention methods for delirium. However, they have limitations because delirium is a condition with a distinct biological basis. Evidence for pharmacological interventions is accumulating, with antipsychotics for treatment and approaches to melatonin neurotransmission and orexin neurotransmission for prevention. Delirium is a sign of poor prognosis, increases the risk of falls and the development of dementia, and increases the medical and economic burden, so the importance of its prevention is increasingly recognized. Pharmacological interventions evolve in this direction, and therapeutic strategies need to develop with the evolving hypothesis of the pathomechanism of delirium.

Journal

Keywords

Details 詳細情報について

  • CRID
    1390018120873657216
  • DOI
    10.11249/jsbpjjpp.35.1_36
  • ISSN
    21866465
    21866619
  • Text Lang
    ja
  • Data Source
    • JaLC
  • Abstract License Flag
    Disallowed

Report a problem

Back to top