A Case of Type 2 Diabetes with Ipragliflozin Administration Developing Euglycemic Diabetic Ketoacidosis Due to Reduced Food Intake Following Colonoscopy
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- Osaki Takamasa
- 波乗りクリニック
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- Tomita Shusaku
- 宇部興産中央病院総合診療科
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- Harada Takahiro
- 宇部興産中央病院総合診療科
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- Matsumoto Shoko
- 宇部興産中央病院総合診療科
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- Saito Hiroyuki
- 山口大学医学部附属病院総合診療部
Bibliographic Information
- Other Title
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- 大腸内視鏡検査後の食事量減少により正常血糖糖尿病性ケトアシドーシスを来したイプラグリフロジン内服中の2型糖尿病の1例
Abstract
<p>The patient was an 80-year-old woman with type 2 diabetes mellitus taking ipragliflozin. She underwent a colonoscopy one week prior to admission. After the colonoscopy, she felt exhausted and lost her appetite. On the day of admission, she was admitted to the emergency department because of abdominal pain and repeated vomiting. Physical examination and chest and abdominal CT were performed; however, no cause was identified for the abdominal pain or vomiting. Blood gas analysis showed high anion gap metabolic acidosis. Serum ketones were elevated to 6,045/μL and plasma glucose concentration was 182 mg/dL. We diagnosed ipragliflozin-induced euglycemic diabetic ketoacidosis (euDKA) and discontinued the drug. Ketoacidosis improved with administration of intravenous fluids and insulin injections. Her abdominal pain and vomiting improved. It is important to recognise that patients taking SGLT2 inhibitors may develop euDKA, as in this case, due to fasting after colonoscopy or reduced food intake after the procedure, and to discontinue SGLT2 inhibitors at least 2 days before the procedure.</p>
Journal
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- An Official Journal of the Japan Primary Care Association
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An Official Journal of the Japan Primary Care Association 47 (1), 12-16, 2024-03-20
JAPAN PRIMARY CARE ASSOCIATION
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Details 詳細情報について
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- CRID
- 1390018130491057792
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- ISSN
- 21872791
- 21852928
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- Text Lang
- ja
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- Data Source
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- JaLC
- Crossref
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- Abstract License Flag
- Disallowed