H-type Hypertension Status and Influencing Factors of the Elderly People Over 80 Years Old Based on Random Forest Model
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- Zhang Xiaobo
- Department of Cardiology Organization, The Second Affiliated Hospital, Harbin Medical University Department of Gerontology, The Fourth Affiliated Hospital, Harbin Medical University
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- Guo Botang
- Department of General Practice, The Affiliated Luohu Hospital of Shenzhen University Health Science Center
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- Zhu Hong
- Department of Health Policy, Health Management College, Harbin Medical University Department of Pharmacy Administration, Humanities and Social Science College, Harbin Medical University
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- Li Dahe
- Department of Gerontology, The Fourth Affiliated Hospital, Harbin Medical University
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- Zhao Yuanyuan
- Department of Gerontology, The Fourth Affiliated Hospital, Harbin Medical University
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- Liu Qi
- Department of Cardiology Organization, The Second Affiliated Hospital, Harbin Medical University The Key Laboratory of Myocardial Ischemia Organization, Chinese Ministry of Education
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- Hou Jingbo
- Department of Cardiology Organization, The Second Affiliated Hospital, Harbin Medical University The Key Laboratory of Myocardial Ischemia Organization, Chinese Ministry of Education
抄録
<p>Hypertension is a common chronic disease in elderly people over 80 years old. Clinically, H-type hypertension occurs when hypertension coexists with hyperhomocysteinemia level of ≥ 10 umol/L. Effective identification of risk factors for H-type hypertension in the elderly can greatly improve patient prognosis.</p><p>Consecutively, 494 patients with hypertension admitted to the Fourth Affiliated Hospital of Harbin Medical University from January 2019 to December 2021 were selected as the study population. They were divided into H-type hypertension (n = 197) and non-H-type hypertension groups (n = 297). Patient data were collected, including basic information, history, and clinical data. The random forest model and LASSO analysis were used to screen the influencing factors for H-type hypertension. Multiple stepwise regression analysis was used to analyze the selected variables.</p><p>A total of 197 elderly people over 80 years old suffered from H-type hypertension, with an incidence rate of 39.88%. The random forest model and LASSO analysis results showed that the top 8 independent variables in importance ranking were ejection fraction (EF), fibrinogen, glycated hemoglobin (HbA1c), B-type natriuretic peptide, creatinine, fasting blood glucose, uric acid, and serum triiodothyronine levels. The results of multivariate analysis showed that EF was the protective factor, while fibrinogen, HbA1c, and creatinine were the risk factors for H-type hypertension in elderly people over 80 years old (P < 0.05).</p><p>Healthcare professionals can indirectly assess the prevalence of H-type hypertension by focusing on EF, fibrinogen, creatinine, and HbA1c in elderly hypertensive patients. This provided proactive intervention and medical services to improve prognosis outcomes.</p>
収録刊行物
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- International Heart Journal
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International Heart Journal 65 (2), 263-270, 2024-03-30
一般社団法人 インターナショナル・ハート・ジャーナル刊行会