Hodgkin Lymphoma-related Inflammatory Modification-displayed Castleman Disease-like Histological Features and Positron Emission Tomography/Computed Tomography Usefulness for the Differential Diagnosis
-
- Yamauchi Hirofumi
- Division of Clinical Oncology and Hematology, Department of Internal Medicine, The Jikei University School of Medicine, Japan
-
- Momoki Mamiko
- Division of Clinical Oncology and Hematology, Department of Internal Medicine, The Jikei University School of Medicine, Japan
-
- Kamiyama Yutaro
- Division of Clinical Oncology and Hematology, Department of Internal Medicine, The Jikei University School of Medicine, Japan
-
- Gunji Tadahiro
- Division of Clinical Oncology and Hematology, Department of Internal Medicine, The Jikei University School of Medicine, Japan
-
- Yokoyama Hiroki
- Division of Clinical Oncology and Hematology, Department of Internal Medicine, The Jikei University School of Medicine, Japan
-
- Saito Takeshi
- Division of Clinical Oncology and Hematology, Department of Internal Medicine, The Jikei University School of Medicine, Japan
-
- Boutboul David
- Department of Clinical Immunology, Hôpital Saint-Louis, Assistance Publique Hôpitaux de Paris (APHP), France
-
- Oksenhendler Eric
- Department of Clinical Immunology, Hôpital Saint-Louis, Assistance Publique Hôpitaux de Paris (APHP), France
-
- Yano Shingo
- Division of Clinical Oncology and Hematology, Department of Internal Medicine, The Jikei University School of Medicine, Japan
Abstract
<p>Hodgkin lymphoma (HL) and idiopathic multicentric Castleman disease (iMCD) are markedly different conditions. However, in some cases, histological similarities caused by elevated cytokines, including interleukin-6, can lead to a misdiagnosis of HL as Castleman disease (CD). We herein report a patient with HL who had been diagnosed with CD by an expert panel and for whom an additional biopsy was useful for determining the correct diagnosis. Furthermore, we analyzed the positron emission tomography/computed tomography findings at the diagnosis and found that the maximum standardized uptake value was useful for distinguishing HL from iMCD. </p>
Journal
-
- Internal Medicine
-
Internal Medicine 63 (7), 993-998, 2024-04-01
The Japanese Society of Internal Medicine