Evaluation of the mechanism of the bone augmentation process for a rat vertical bone augmentation model using polytetrafluoroethylene tubes

DOI
  • YANO Makiko
    Graduate School of Dentistry (Department of Orthodontics), Osaka Dental University
  • YASUI Kenichirou
    Department of Orthodontics, Osaka Dental University
  • OKAMORI Daisuke
    Graduate School of Dentistry (Department of Orthodontics), Osaka Dental University
  • INOUE Aya
    Graduate School of Dentistry (Department of Orthodontics), Osaka Dental University
  • KISHIKAWA Minoru
    Graduate School of Dentistry (Department of Orthodontics), Osaka Dental University
  • ADACHI Takeryo
    Graduate School of Dentistry (Department of Orthodontics), Osaka Dental University
  • TAKASUGI Sara
    Graduate School of Dentistry (Department of Orthodontics), Osaka Dental University
  • KUBOTA Tsutomu
    Department of Biomaterials, Osaka Dental University
  • HASHIMOTO Yoshiya
    Department of Biomaterials, Osaka Dental University
  • MATSUMOTO Naoyuki
    Department of Orthodontics, Osaka Dental University

Abstract

<p>In this study, based on a model of vertical bone augmentation in a rat skull using polytetrafluoroethylene (PTFE) tubes, two bioabsorbable bone replacement materials, carbonate apatite (CytransR granules, CGs), and β‐tricalcium phosphate (β‐TCP), were placed in the center of the skull. Bone augmentation was performed by transplanting CGs or β‐TCP in a PTFE tube placed at the center of the skull. Specimens were collected along with the surrounding tissue at 4, 8 and 12 weeks postoperatively for radiographic and histological evaluation. There was no significant difference in the number or spacing of osteophytes in the material‐transplant groups, and there was no difference in the quality of the new bone. Although the time of appearance of osteoclasts was the same for both materials, more osteoblasts appeared earlier and bone formation occurred earlier with the β‐TCP granules, which were absorbed earlier than with the CGs. (J Osaka Dent Univ 2024; 58: 339-348)</p>

Journal

Keywords

Details 詳細情報について

  • CRID
    1390018451149587968
  • DOI
    10.18905/jodu.58.1_339
  • ISSN
    21896488
    04752058
  • Text Lang
    en
  • Data Source
    • JaLC
  • Abstract License Flag
    Disallowed

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