マンナンスムージーの食物繊維がメタボリックシンドローム発症ラットの メタボリックシンドローム発症を予防する

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タイトル別名
  • Dietary fiber from mannan smoothie prevents metabolic syndrome development in metabolic syndrome-prone rats
公開日
2024-04-29
DOI
  • 10.18891/jjfcs.31.1_21
公開者
日本食品化学学会

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説明

Metabolic syndrome is an increasingly prevalent health concern comprising multiple metabolic perturbations that can lead to life-threatening diseases if uncontrolled. Apart from physical activity, one way to control metabolic syndrome is by incorporating fiber-rich foods, such as konjac potato, into the diet. The present study examined the effects of Mannan Smoothie (MS), a modified konjac potato product, on metabolic syndrome-prone OLETF (Otsuka Long Evans Tokushima Fatty) rats. OLETF rats were fed standard chow mixed with 30% MS or standard chow only for 10 weeks (n=12 for each group). Compared with OLETF rats fed on standard chow (n=12), MS-fed OLETF rats had similar food intake, but 34% less body weight gain (p＜0.01). Abdominal fat was significantly lower in the MS group compared with the control group. MS feeding also resulted in significantly lower postprandial blood glucose and insulin levels compared with the control group (119 ± 16 mg/dL vs. 138 ± 21 mg/dL, respectively, p＜0.05). Finally, MS feeding was associated with significantly higher gut weight and villus height compared with the control group. Overall, these data suggest that dietary fiber from MS has the potential to maintain body weight, regulate blood glucose, and improve gut morphology in subjects with metabolic syndrome.

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