Evaluation of the effect of postoperative radiotherapy for locoregional control in salivary gland cancer

DOI Web Site 9 References
  • Kano Satoshi
    Department of Otolaryngology-Head and Neck Surgery, Faculty of Medicine and Graduate School of Medicine, Hokkaido University
  • Tsushima Nayuta
    Department of Otolaryngology-Head and Neck Surgery, Faculty of Medicine and Graduate School of Medicine, Hokkaido University
  • Suzuki Takayoshi
    Department of Otolaryngology-Head and Neck Surgery, Faculty of Medicine and Graduate School of Medicine, Hokkaido University
  • Hamada Seijiro
    Department of Otolaryngology-Head and Neck Surgery, Faculty of Medicine and Graduate School of Medicine, Hokkaido University
  • Yasuda Koichi
    Department of Radiation Oncology, Faculty of Medicine and Graduate School of Medicine, Hokkaido University
  • Uchinami Yusuke
    Department of Radiation Oncology, Faculty of Medicine and Graduate School of Medicine, Hokkaido University
  • Homma Akihiro
    Department of Otolaryngology-Head and Neck Surgery, Faculty of Medicine and Graduate School of Medicine, Hokkaido University

Bibliographic Information

Other Title
  • 唾液腺癌の局所頸部制御における術後照射の有用性の検討

Abstract

We examined retrospectively the effect of postoperative radiotherapy for salivary gland cancer performed at our hospital. There were 104 eligible patients, of whom 75 （72％） received postoperative radiotherapy. For all patients, the 3-year locoregional control （LRC） rate was 90.3％ （95％ CI 82.8-97.9％） in the group with postoperative radiotherapy and 71.2％ （95％ CI 52.9-89.5％） in the group without postoperative radiotherapy, and was thus significantly better in the group with postoperative radiotherapy （p＝0.02）. For the patients with parotid gland cancers, the 3-year local control （LC） rate was 93.0％ （95％ CI 86.4-99.7％） in the group with postoperative radiotherapy and 66.6％ （95％ CI 42.4-90.9％） in the group without postoperative radiotherapy （p＜0.01）. Multivariate analysis showed that postoperative radiotherapy was the only independent risk factor in LRC for all patients, and in the analysis of parotid gland cancers, high grade malignancy and postoperative radiotherapy were independent risk factors in LC.

Journal

  • Toukeibu Gan

    Toukeibu Gan 50 (1), 6-12, 2024

    Japan Society for Head and Neck Cancer

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