Efficacy of Probiotic Formulation for Chronic Constipation in Elderly

DOI
  • Asaoka Daisuke
    Department of Gastroenterology, Juntendo Tokyo Koto Geriatric Medical Center
  • Takeda Tsutomu
    Department of Gastroenterology, Juntendo Tokyo Koto Geriatric Medical Center
  • Ikeda Atsushi
    Department of Gastroenterology, Juntendo Tokyo Koto Geriatric Medical Center
  • Yamamoto Momoko
    Department of Gastroenterology, Juntendo Tokyo Koto Geriatric Medical Center
  • Otsuki Yudai
    Department of Gastroenterology, Juntendo Tokyo Koto Geriatric Medical Center
  • Taniguchi Gentaro
    Department of Gastroenterology, Juntendo Tokyo Koto Geriatric Medical Center
  • Iwano Tomoyo
    Department of Gastroenterology, Juntendo University School of Medicine
  • Uchida Ryota
    Department of Gastroenterology, Juntendo University School of Medicine
  • Utsunomiya Hisanori
    Department of Gastroenterology, Juntendo University School of Medicine
  • Oki Shotaro
    Department of Gastroenterology, Juntendo University School of Medicine
  • Suzuki Nobuyuki
    Department of Gastroenterology, Juntendo University School of Medicine
  • Abe Daiki
    Department of Gastroenterology, Juntendo University School of Medicine
  • Akazawa Yoichi
    Department of Gastroenterology, Juntendo University School of Medicine
  • Ueda Kumiko
    Department of Gastroenterology, Juntendo University School of Medicine
  • Ueyama Hiroya
    Department of Gastroenterology, Juntendo University School of Medicine
  • Hojo Mariko
    Department of Gastroenterology, Juntendo University School of Medicine
  • Nagahara Akihito
    Department of Gastroenterology, Juntendo University School of Medicine

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Other Title
  • 高齢者の慢性便秘症に対するプロバイオティクス製剤の治療効果に関する検討

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<p>Probiotic formulations were administered to elderly patients with chronic constipation, and the results were evaluated using modified Constipation Scoring System (mCSS), which excludes "duration of symptoms" from the CSS evaluation items. Improvement was observed in "frequency of bowel movement", "feeling incomplete evacuation", "abdominal pain", "minutes in lavatory per attempt", "unsuccessful attempts at evacuation per 24 hours", and "mCSS total score" and BSS approached to 4 points that were an ideal stool property. Among the patients, those whose total mCSS score improved (decreased) by 4 points or more (⊿mCSS≥4 group) had a higher score than those whose total mCSS score improved by <4 points (⊿mCSS<4 group) in "feeling incomplete evacuation", "residual stool sensation" and "epigastric burning sensation".</p>

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