化粧品原料としての幹細胞培養上清液利用技術開発―産学連携による地域貢献―

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  • ケショウヒン ゲンリョウ トシテ ノ カンサイボウジョウセイエキ リヨウ ギジュツ カイハツ ― サンガク レンケイ ニヨル チイキ コウケン ―

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“Stem cell conditioned media” is obtained from the specialized culture media in which stem cells, such as those derived from umbilical cord blood, adipose tissue, or dental pulp, are cultured. After the cultivation process, stem cells are removed from the medium, and the remaining liquid is subjected to sterilization processes. Stem cells not only have the ability to differentiate into various types of cells but also produce signaling molecules that regulate cellular biological activity, as well as growth factors that promote cellular proliferation. These factors diffuse through interstitial fluid rather than through the bloodstream (paracrine signaling). Hence, the culture supernatant is also rich in bioactive factors. Due to these properties, stem cell conditioned media are expected to contribute to the development of new therapeutic technologies, by the activation of epithelial tissues. For example, when applied directly to the scalp, it is anticipated that the activation of hair follicle stem cells may prevent or improve AGA (AndroGenetic Alopecia). The Aim of this study is to investigate, from a cell physiology perspective, whether the culture supernatant derived from “human scalp stem cells (hair follicle stem cells)” ― which have been uniquely identified by our research partner, Horus Co. Ltd. ― induces hair regeneration through the activation of the tissue surrounding the hair follicle or the conversion of gray hair to black hair through the resolution of pigment cell dysfunction.

論文 / Article 編集:城西大学・城西短期大学地域連携センター紀要編集委員会

source:Journal of Josai Community Liaison Center

identifier:JOS-24362336-0505

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