Simultaneous determination of bisphenol A and alkylphenols by LC/atmospheric pressure-ionization MS.

TAKINO Masahiko, DAISHIMA Shigeki, YAMAGUCHI Kenji

doi:10.2116/bunsekikagaku.48.563

Bibliographic Information

Other Title

液体クロマトグラフィー／大気圧イオン化質量分析法によるビスフェノールＡ及びアルキルフェノール類の一斉分析
エキタイクロマトグラフィータイキアツイオンカシツリョウブンセキホウニヨルビスフェノール A オヨビアルキルフェノールルイノイッセイブンセキ
液体クロマトグラフィー/大気圧イオン化質量分析法によるビスフェノールA及びアルキルフェノール類の一斉分析 (<特集>環境ホルモンと分析化学)

Search this article

Description

An analytical method for the determination of bisphenol A and alkylphenols with liquid chromatography/mass spectrometry (LC/MS) has been developed. Under reversed-phase liquid-chromatographic conditions, bisphenol A and seven alkylphenols have been analyzed using atmospheric-pressure chemical ionization (APCI) and electrospray ionization (ESI) methods. The effects of post-column modification of the liquid chromatographic mobile phase, the fragmentor voltage with ESI methods and the temperature of the vaporizer with APCI methods on the sensitivity for the detection of bisphenol A and alkylphenols were examined. The sensitivities of the APCI methods were higher than those of the ESI methods. Large volumes of river water samples were directly injected into the precolumn, and then bisphenol A and alkylphenols were separated by an analytical column with a column-switching technique. The limit of detection (LOD) of these phenols ranged from 5 ppt to 20 ppt. The overall recoveries of phenols were from 93.0 to 112.4% {RSD (n=5) from 2.1 to 5.3%} for river water.

Journal

BUNSEKI KAGAKU

BUNSEKI KAGAKU 48 (6), 563-570, 1999

The Japan Society for Analytical Chemistry

Keywords

Details 詳細情報について

Export

Report a problem