Progresses in separation and sensing technologies using DNA as affinity ligands (Review).

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  • UMENO Daisuke
    Department of Materials Physics and Chemistry, Graduate School of Engineering, Kyushu University
  • MAEDA Mizuo
    Department of Materials Physics and Chemistry, Graduate School of Engineering, Kyushu University

Bibliographic Information

Other Title
  • 遺伝子ＤＮＡをアフィニティーリガンドとする分離・計測法の進歩
  • イデンシ DNA オ アフィニティー リガンド ト スル ブンリ ケイソクホウ ノ シンポ

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Abstract

The recent developments of affinity techniques concerning single- and double-stranded DNA are reviewed. Based on the opinion that the immobilization of DNA is essential for the analytical and preparative use of the ligand function of DNAs, the two items are extensively discussed concerning the choice of conjugation chemistry and supports. Finally, a variety of applications, mainly for sensing and purification, are discussed.

Journal

  • BUNSEKI KAGAKU

    BUNSEKI KAGAKU 48 (10), 871-890, 1999

    The Japan Society for Analytical Chemistry

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