Quality control of traditional chinese drugs by high performance liquid chromatography.

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Other Title
  • 高速液体クロマトグラフィーによる漢方製剤の品質管理
  • コウソク エキタイ クロマトグラフィー ニ ヨル カンポウ セイザイ ノ ヒン
  • 高速液体クロマトグラフィーによる漢方製剤の品質管理(<特集>医薬品の分析)

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Abstract

A quantitative quality control method of traditional chinese drugs (TCD) by HPLC is described, by choosing Mao-to formulation as an example of TCD. Six compounds, namely l- and d-ψ-ephedrine, amygdalin, cinnamaldehyde, glycyrrhizin and liquiritin specific to each of four constituent crude drugs of the formulation (Ephedrae Herba, Armeniacae Semen, Cinnamomi Cortex, Glycyrrhizae Radix) were used as reference substances. These compounds present in crude drugs as well as in processed preparations could be precisely assayed on an ODS column using four different mobile phases. In addition, it was stated that HPLC is similarly applicable to determination of some compounds specific to other several crude drugs than the above-mentioned ones.

Journal

  • BUNSEKI KAGAKU

    BUNSEKI KAGAKU 35 (3), 202-206, 1986

    The Japan Society for Analytical Chemistry

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