Recent Advance in Structural Studies under Extreme Conditions. Rapid Data Collection of Protein Crystals with Laue Diffraction Method.
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- ADACHI Shin-ichi
- Biophysical Chemistry Laboratory, The Institute of Physical and Chemical Research (Riken) Harima Institute
Bibliographic Information
- Other Title
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- 特殊条件下の構造研究の新展開 白色ラウエ法によるたん白結晶の迅速測定
- ハクショク ラウエホウ ニ ヨル タンパク ケッショウ ノ ジンソク ソクテイ
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Abstract
With the use of extremely intense synchrotron radiation sources it has become possible to collect good quality x-ray diffraction data for protein crystals on a subsecond time-scale. This has led to the development of time-resolved protein crystallography, where the main objective is to determine the structures of short-lived intermediates during enzymatic reactions by monitoring the time dependence of the x-ray intensities. Furthermore, utilization of singlebunch mode at the third generation synchrotron sources enables us to shorten the time-scale of the time-resolved protein crystallography down to nanosecond order. Feasibility of singlepulse Laue diffraction experiment on protein crystals is discussed.
Journal
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- Nihon Kessho Gakkaishi
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Nihon Kessho Gakkaishi 41 (1), 92-97, 1999
The Crystallographic Society of Japan
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Details 詳細情報について
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- CRID
- 1390282679063094528
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- NII Article ID
- 10002591538
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- NII Book ID
- AN00188364
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- ISSN
- 18845576
- 03694585
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- NDL BIB ID
- 4672643
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- Text Lang
- ja
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- Data Source
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- JaLC
- NDL
- Crossref
- CiNii Articles
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- Abstract License Flag
- Disallowed